Pittsburgh, PANCT06626334Now EnrollingIRB Ready

Rib Fractures Clinical Trial in Pittsburgh, PA

Access cutting-edge rib fractures treatment through this clinical trial at a research site in Pittsburgh. Study-provided care at no cost to qualified participants.

Sponsored by Rebecca E Kotcher, MD

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Expert Care in Pittsburgh

Access rib fractures specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related rib fractures treatment provided free

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Check if you qualify for this rib fractures clinical trial in Pittsburgh, PA

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Why Participate?

  • No-Cost Study Care

  • Local to Pittsburgh

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pittsburgh site if eligible
  4. 4Begin participation

About This Rib Fractures Study in Pittsburgh

The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures. The main question it aims to answer is: \- Does bright blue light therapy in addition to standard pain treatments improve pain with breathing in adults with painful rib fractures? Researchers will compare participants who receive bright blue light therapy to participants who receive white light therapy and participants who receive only usual lighting conditions to look for differences in their pain control. In addition to their assigned light treatment, all participants will receive standard pain control treatments. Participants will be assigned randomly to one of three groups: one-third will be assigned to bright blue light therapy, one-third will be assigned to bright white light therapy, and one-third will be assigned to usual light only. They will receive their assigned light treatment for 4 hours during the morning/early afternoon for up to 3 days while they are in the hospital. On each day they receive the light treatment and on the day after their final light treatment: * They will be asked twice to rate their pain at rest and with taking a deep breath. * They will be tested to confirm that they are not experiencing delirium, or confusion related to being in the hospital. * Blood samples will be collected to look for changes in inflammation and the circadian clock, the body's natural 24-hour cycle.

Sponsor: Rebecca E Kotcher, MD

Who Can Participate

Inclusion Criteria

Age greater than or equal to 18 years
Admitted to a single large academic level I trauma center (Presbyterian/Montefiore hospital) within the first 48 hours of traumatic injury
Greater than or equal to 1 acute rib fracture
Pain related to rib fracture(s), by one or more of the following criteria: 1. Pain \>/= 4/10 at rest, 2. Pain \>/= 4/10 with incentive spirometer (IS) use, and/or 3. Inspiratory volume \< 1000 cc
Anticipated length of stay greater than or equal to 48 hours
Alert, with capacity to provide informed consent

Exclusion Criteria

Mechanical ventilation\
or non-invasive positive pressure ventilation administered for respiratory insufficiency prior to the time of informed consent
Delirium (positive CAM screening) at the time of informed consent
Ocular trauma, which may interfere with the mechanism of action
Traumatic brain injury (TBI) or history of TBI or stroke, which may interfere with the mechanism of action
Splenectomy upon admission or history of splenectomy, which may interfere with the mechanism of action
History of significant ocular dysfunction\*\
(i.e., macular degeneration, glaucoma, cataracts), which may interfere with the mechanism of action
History of cataract surgery, due to the possibility of blue light filtering intraocular lens placement
History of bipolar disorder or schizophrenia, which could increase the risk of an adverse reaction to light exposure (i.e., acute mania)
History of dementia, which would compromise the reliability of pain intensity and delirium measures
Or other condition in which a patient cannot open eyes to receive light intervention or report a pain score \*\*Myopia, hyperopia, and/or astigmatism corrected for with contact lenses or spectacle corrective eyeglasses will NOT be a criterion for exclusion

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pittsburgh?

Yes, this clinical trial (NCT06626334) has an active research site in Pittsburgh, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Rib Fractures Treatment Options in Pittsburgh, PA

If you're searching for rib fractures treatment options in Pittsburgh, PA, this clinical trial (NCT06626334) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pittsburgh research site is actively enrolling participants for this clinical trial. You'll receive care from experienced rib fractures specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all rib fractures clinical trials near you to find additional studies recruiting in your area.

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