The Bronx, NYNCT07725380Now EnrollingIRB Ready

Sarcoma Clinical Trial in The Bronx, NY

Access cutting-edge sarcoma treatment through this phase 1/2 clinical trial at a research site in The Bronx. Study-provided care at no cost to qualified participants.

Sponsored by H. Lee Moffitt Cancer Center and Research Institute

Quick Self-Assessment

See if you qualify for this The Bronx location

Preparing your pre-screening questions…

Expert Care in The Bronx

Access sarcoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related sarcoma treatment provided free

Apply for This The Bronx Location

Check if you qualify for this sarcoma clinical trial in The Bronx, NY

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to The Bronx

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit The Bronx site if eligible
  4. 4Begin participation

About This Sarcoma Study in The Bronx

This is a multicenter, open-label, Phase 1/2 study evaluating the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of domatinostat in combination with sirolimus in adolescents and adults with relapsed or refractory sarcoma and osteosarcoma.

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Who Can Participate

Inclusion Criteria

Age ≥12 and ≤40 years.
Histologically confirmed relapsed or refractory sarcoma (Phase 1) or osteosarcoma (Phase 2).
At least one prior standard systemic therapy regimen.
Not candidates for available therapies known to provide survival benefit.
Karnofsky/Lansky performance score ≥60.
Life expectancy ≥16 weeks.
Adequate organ function: ANC ≥1,000/mcL, Platelets ≥100,000/uL, Hemoglobin ≥8 g/dL, Adequate hepatic and renal function.
Ability to swallow tablets.
Negative pregnancy test for females of childbearing potential.
Agreement to use effective contraception.
Ability to provide informed consent/assent.

Exclusion Criteria

Receiving another investigational agent.
Receiving concurrent anticancer therapy.
Known hypersensitivity to domatinostat or sirolimus.
Bone marrow-only disease.
CNS metastatic disease.
Major surgery within 2 weeks prior to treatment.
Active malignancy within the previous 3 years (with protocol-specified exceptions).
History of solid organ transplantation.
Significant recent cardiac disease.
Concurrent prohibited CYP3A4/P-gp interacting medications.
Uncontrolled infection or other serious uncontrolled illness.
Pregnancy or breastfeeding.
HIV infection on antiretroviral therapy.
Weight \<40 kg.
Inability to comply with study requirements.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in The Bronx?

Yes, this clinical trial (NCT07725380) has an active research site in The Bronx, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Sarcoma Treatment Options in The Bronx, NY

If you're searching for sarcoma treatment options in The Bronx, NY, this clinical trial (NCT07725380) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our The Bronx research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced sarcoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all sarcoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · The Bronx, NY