Worcester, MANCT06174116Now EnrollingIRB Ready

Schizophrenia Clinical Trial in Worcester, MA

Access cutting-edge schizophrenia treatment through this phase 4 clinical trial at a research site in Worcester. Study-provided care at no cost to qualified participants.

Sponsored by University of Massachusetts, Worcester

Quick Self-Assessment

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Expert Care in Worcester

Access schizophrenia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related schizophrenia treatment provided free

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Check if you qualify for this schizophrenia clinical trial in Worcester, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Worcester

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Worcester site if eligible
  4. 4Begin participation

About This Schizophrenia Study in Worcester

The main question this study is trying to answer is whether lumateperone, an FDA-approved antipsychotic drug, can help reduce possible side effects of clozapine, such as weight gain and elevated levels of sugar and bad cholesterol. Participants will be randomly assigned to either take lumateperone (Caplyta) or a placebo for 12 weeks, in addition to their regularly prescribed clozapine. During their participation, patients will answer questions about their psychiatric and daily functioning, have blood drawn, and have their body composition analyzed (similar to stepping on a scale).

Sponsor: University of Massachusetts, Worcester

Who Can Participate

Inclusion Criteria

Meets the DSM-5 criteria for diagnoses of schizophrenia or schizoaffective disorder based on the MINI International Neuropsychiatric Interview (MINI 7.0)
On clozapine treatment for at least 6 months
Stable dose of antipsychotic treatment for at least 1 month
Well established compliance with outpatient medications
Subjects of child-bearing potential are required to practice appropriate birth control methods during the study.

Exclusion Criteria

Psychiatrically unstable per clinical judgement by the principal investigator
Patients not on stable dose of antipsychotic medications
Currently meets DSM-5 criteria for any substance use disorder other than caffeine and nicotine
Significant, unstable medical conditions including severe cardiovascular, hepatic, renal or other medical diseases
History of a seizure disorder
Pregnancy or breastfeeding
On lumateperone treatment in the past 3 months
On a dopamine partial agonist antipsychotic agent in the past 3 months (aripiprazole, brexpiprazole, cariprazine)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Worcester?

Yes, this clinical trial (NCT06174116) has an active research site in Worcester, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Schizophrenia Treatment Options in Worcester, MA

If you're searching for schizophrenia treatment options in Worcester, MA, this clinical trial (NCT06174116) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Worcester research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced schizophrenia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all schizophrenia clinical trials near you to find additional studies recruiting in your area.

More Schizophrenia Trials in Worcester, MA

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Secure · Expert Care · Worcester, MA