Charleston, SCNCT05855369Now EnrollingIRB Ready

Smell Dysfunction Clinical Trial in Charleston, SC

Access cutting-edge smell dysfunction treatment through this phase 2/3 clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by Medical University of South Carolina

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Expert Care in Charleston

Access smell dysfunction specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related smell dysfunction treatment provided free

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Check if you qualify for this smell dysfunction clinical trial in Charleston, SC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Smell Dysfunction Study in Charleston

Persistent smell loss that can include diminished or distorted smell function is a common symptom of long COVID syndrome. There are limited treatment options for long COVID-related smell loss. This study aims to determine the efficacy of two at-home treatments, smell training and non-invasive trigeminal nerve stimulation. This study requires participants to conduct daily at-home treatment sessions, attend three in-person study visits at the MUSC Department of Psychiatry and Behavioral Sciences, and complete electronic questionnaires over the 12-week trial, and again at the six-month timepoint. Participants in this trial may benefit directly with an improvement in sense of smell. However, participation may also help society more generally, as this study will provide new information about long COVID-related smell loss and its treatment.

Sponsor: Medical University of South Carolina

Who Can Participate

Inclusion Criteria

treatment-seeking for COVID-related persistent SL (anosmia, hyposmia, phantosmia or parosmia)
at least 1-month from SARS-coV-2 PCR-positive and/or rapid home-positive tests
normal sense of smell prior to COVID
naïve to both smell training (ST) and trigeminal nerve stimulation (TNS)
able to comprehend English and provide informed consent

Exclusion Criteria

history of head injury (e.g. sport, accident, combat blast)
sinonasal condition (e.g. upper respiratory infection, rhinosinusitis, polyps)
neurological disorder (e.g. epilepsy, neurodegenerative disorder, narcolepsy)
serious mental illness (e.g. schizophrenia, bipolar, or other psychotic disorder)
suicidal ideation within the last month
current (≤6 months) heavy cigarette smoker (heavy defined as ≥ 10 pack-years)
oral/nasal steroids or other intranasal medications within the last month
immunomodulatory medications
pregnant or trying to become pregnant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT05855369) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Smell Dysfunction Treatment Options in Charleston, SC

If you're searching for smell dysfunction treatment options in Charleston, SC, this clinical trial (NCT05855369) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this phase 2/3 clinical trial. You'll receive care from experienced smell dysfunction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all smell dysfunction clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC