Orange, CANCT06824363Now EnrollingIRB Ready

Solid Tumor, Adult Clinical Trial in Orange, CA

Access cutting-edge solid tumor, adult treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by University of California, Irvine

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions…

Expert Care in Orange

Access solid tumor, adult specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related solid tumor, adult treatment provided free

Apply for This Orange Location

Check if you qualify for this solid tumor, adult clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Solid Tumor, Adult Study in Orange

This is a proof of principle clinical trial determining efficacy of single dose dualimmune checkpoint inhibitors to increase intra-tumoral T cells in esophageal, gastroesophageal junction, and gastric adenocarcinomas. These are subjects who have not previously been treated for their disease, who are willing to undergo biopsy procedures, who's disease has not spread to other parts of the body, who's tumors have ARID1A mutations.

Sponsor: University of California, Irvine

Who Can Participate

Inclusion Criteria

Non metastatic GEC including locally advanced unresectable
Treatment naïve
Histologically proven adenocarcinoma of the esophagus or the stomach with ARID1a mutation either by liquid biopsy (ctDNA) or tissue NGS/WES
MSI-Stable or pMMR
Age ≥ 18 years
Body weight \> 66 pounds
Repeat biopsy feasible
No clinically significant autoimmune disease

Exclusion Criteria

Patients with known metastatic disease
Prior systemic treatment for esophagus, GEJ, or the stomach adenocarcinoma
Patients with uncontrolled autoimmune disease per investigator discretion
Inability or refusal to undergo biopsy procedures to obtain tissue samples

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT06824363) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Solid Tumor, Adult Treatment Options in Orange, CA

If you're searching for solid tumor, adult treatment options in Orange, CA, this clinical trial (NCT06824363) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced solid tumor, adult specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all solid tumor, adult clinical trials near you to find additional studies recruiting in your area.

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Ready to Join in Orange?

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Secure · Expert Care · Orange, CA