Huntersville, NCNCT04900818Now EnrollingIRB Ready

Solid Tumor Clinical Trial in Huntersville, NC

Access cutting-edge solid tumor treatment through this clinical trial at a research site in Huntersville. Study-provided care at no cost to qualified participants.

Sponsored by I-Mab Biopharma US Limited

Quick Self-Assessment

See if you qualify for this Huntersville location

Preparing your pre-screening questions…

Expert Care in Huntersville

Access solid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related solid tumor treatment provided free

Apply for This Huntersville Location

Check if you qualify for this solid tumor clinical trial in Huntersville, NC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Huntersville

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Huntersville site if eligible
  4. 4Begin participation

About This Solid Tumor Study in Huntersville

This is an open label, multi-center, multiple dose Phase 1 study to evaluate the safety, tolerability, MTD PK, and PD of TJ033721 (givastomig) in subjects with advanced or metastatic solid tumors.

Sponsor: I-Mab Biopharma US Limited

Who Can Participate

Inclusion Criteria

Part 1 - Monotherapy Subjects with advanced or metastatic solid tumor in subjects whose disease has progressed despite standard therapy, or who has no further standard therapy, or who is unsuitable for available standard treatment options. Part 2 - Combination Therapy Subjects with treatment naïve locally advanced, unresectable or metastatic gastric, GEJ, esophageal adenocarcinoma; Part 3: Combination Therapy Subjects with unresectable, locally advanced or metastatic histologically confirmed pancreatic adenocarcinoma; Part 4: Combination Therapy Subjects with unresectable, locally advanced or metastatic histologically confirmed biliary tract cancer.
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1 with adequate organ function
Have known PD-L1 status with prior testing by immunohistochemistry and a corresponding combined positive score (CPS) For dose expansion and Part 2, Part 3, Part 4 Combination subjects: • Must have CLDN18.2-positive tumor expression

Exclusion Criteria

Prior exposure to CLDN18.2 -targeted therapy
Prior exposure to 4-1BB agonists
Second malignancy within the last 3 years with the exception of cutaneous squamous cell carcinoma or cutaneous basal cell carcinoma or cervical carcinoma in situ
Known active or chronic Hepatitis B or Hepatitis C, other hepatitides
Unstable/active ulcer or digestive tract bleeding within 6 weeks
Active autoimmune disease requiring systemic treatment within the past 2 years
Active interstitial lung disease (ILD) or pneumonitis or a history of ILD or pneumonitis requiring treatment
Known active CNS metastases and/or carcinomatous meningitis. Subjects with previously treated brain metastases may participate provided they are clinically stable and without requirement of steroid treatment for at least 14 days prior to first dose of study treatment;
New York Heart Association (NYHA) Class 3 or 4 congestive heart failure, severe/unstable angina, myocardial infarction (MI), symptomatic congestive heart failure, cerebrovascular accident, transient ischemic attack (TIA), arterial embolism, percutaneous transluminal coronary angioplasty (PTCA), or coronary artery bypass grafting (CABG) in the previous 6 months
Diagnosis of immunodeficiency such as known active HIV
Any active infection requiring parenteral treatment For Part 2, 3, 4 Combination subjects: • Prior treatment with anti-PD-1 or PD-L1 agent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Huntersville?

Yes, this clinical trial (NCT04900818) has an active research site in Huntersville, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Solid Tumor Treatment Options in Huntersville, NC

If you're searching for solid tumor treatment options in Huntersville, NC, this clinical trial (NCT04900818) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Huntersville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced solid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all solid tumor clinical trials near you to find additional studies recruiting in your area.

More Advanced Solid Tumors Trials in Huntersville, NC

See all advanced solid tumors clinical trials recruiting in Huntersville — not just this study.

Browse Advanced Solid Tumors Trials in Huntersville →

Browse More Trials by Condition

Advanced Solid Tumors TrialsAll Conditions →

Ready to Join in Huntersville?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Huntersville, NC