Orange, CANCT02446431Now EnrollingIRB Ready

Solid Tumor Clinical Trial in Orange, CA

Access cutting-edge solid tumor treatment through this clinical trial at a research site in Orange. Study-provided care at no cost to qualified participants.

Sponsored by Miller Children's & Women's Hospital Long Beach

Quick Self-Assessment

See if you qualify for this Orange location

Preparing your pre-screening questions…

Expert Care in Orange

Access solid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related solid tumor treatment provided free

Apply for This Orange Location

Check if you qualify for this solid tumor clinical trial in Orange, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orange

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orange site if eligible
  4. 4Begin participation

About This Solid Tumor Study in Orange

Most pediatric patients with solid tumors respond to initial high-dose, intensive therapy and complete treatment in remission. High-risk patients however, frequently have recurrent disease which is then treated with ad hoc regimens or early phase therapies with little benefit to the patient. Metronomic therapy (MC), defined as lower dose continuous drug exposure, has been successfully tested in pediatric leukemias with excellent results in terms of improved outcome, toxicity profiles, and cost. MC has been applied to solid tumors with little success, but has been implemented usually in the relapsed setting at a time of high tumor burden and disease resistance.

Sponsor: Miller Children's & Women's Hospital Long Beach

Who Can Participate

Inclusion Criteria

The following solid tumors will be studied: rhabdomyosarcoma, osteosarcoma, Ewing sarcoma, other soft tissue sarcomas
Other solid tumors fulfilling the remainder of eligibility criteria and available historical data to determine time to tumor progression
Expected time to progression of \< 2 years, based on historical data
All patients will have completed front-line therapy
All patients will be in remission from their primary diagnosis
All patients will start metronomic therapy within 6 weeks of completion of front-line treatment
All patient will have recovered from previous toxicities
All patients or their parents/legal guardian will have signed an informed consent document
All institutional eligibility criteria will be meet
Age: Patients must be ≥ 12 months and \<31 years of age at the time of study entry
Patients must have had histologic verification of malignancy at original diagnosis
Patients must have a Lansky or Karnofsky performance status score of ≥ 50, corresponding to ECOG categories 0, 1 or 2.
Adequate renal function defined as: Normal serum creatinine
Normal liver tests (ALT/AST/total bilirubin/triglycerides/cholesterol)
Recovered from all surgical procedures for at least 7 days (minor procedures) or 28 days (major procedures)
Adequate cardiac function defined as: Shortening fraction of ≥ 27% by echocardiogram, or ejection fraction of ≥ 50% by radionuclide angiogram
Platelet count 100,000K/uL (transfusion independent), hemoglobin 8.0 g/dL
Adequate bone marrow function: Peripheral absolute neutrophil count (ANC) 1,000K/uL
Signed Informed Consent document and/or Assent document

Exclusion Criteria

Female patients who are pregnant
Lactating females are not eligible unless they have agreed to discontinue breastfeeding
Female patients of childbearing potential are not eligible unless a negative pregnancy test result has been obtained
Sexually active patients of reproductive potential are not eligible unless they have agreed to use an effective contraceptive method for the duration of study participation
Any primary central nervous system tumor
Any patient who has experienced relapsed or refractory disease or a second malignancy.
Any patient not in remission

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orange?

Yes, this clinical trial (NCT02446431) has an active research site in Orange, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Solid Tumor Treatment Options in Orange, CA

If you're searching for solid tumor treatment options in Orange, CA, this clinical trial (NCT02446431) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orange research site is actively enrolling participants for this clinical trial. You'll receive care from experienced solid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all solid tumor clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Orange, CA