Downey, CANCT06841770Now EnrollingIRB Ready

Spinal Cord Injury Cervical Clinical Trial in Downey, CA

Access cutting-edge spinal cord injury cervical treatment through this clinical trial at a research site in Downey. Study-provided care at no cost to qualified participants.

Sponsored by Lineage Cell Therapeutics, Inc.

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Expert Care in Downey

Access spinal cord injury cervical specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related spinal cord injury cervical treatment provided free

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Check if you qualify for this spinal cord injury cervical clinical trial in Downey, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Downey

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Downey site if eligible
  4. 4Begin participation

About This Spinal Cord Injury Cervical Study in Downey

The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI). LCTOPC1 is designed to replace or support cells that are absent or dysfunctional due to traumatic injury, with a goal to help improve the quality of life and restore or augment functional activity in persons suffering from a traumatic cervical or thoracic injuries.

Sponsor: Lineage Cell Therapeutics, Inc.

Who Can Participate

Inclusion Criteria

Sensorimotor complete, traumatic SCI (ASIA Impairment Scale A) or sensory incomplete, traumatic SCI (ASIA Impairment Scale B)
For subjects with subacute injury, International Standards for Neurological Classification of SCI (ISNCSCI) Neurological Level of Injury (NLI) from C-4 to T-10 occurring 21 to 42 days prior to LCTOPC1 injection
For subjects with chronic injury, ISNCSCI NLI from C-4 to T-10 and more than 30 days without clinical improvement from last assessment, occurring 1 to 5 years prior to LCTOPC1 injection
Individuals must have at least one upper extremity ISNCSCI key muscle with at least 1/5 strength
18 through 65 years of age, inclusive, at time of consent
Single injury with sufficient visualization of the spinal cord injury epicenter and lesion margins to enable post-injection safety monitoring
Informed consent for this protocol must be provided and documented (i.e., signed ICF)
Able to participate in an elective surgical procedure to inject LCTOPC1 21 days or later following SCI
Female subjects of child-bearing potential must agree to the use of contraception for 1 year following LCTOPC1 injection; male subjects must agree to use contraception to prevent pregnancy in any female partners of child-bearing potential for 1 year following LCTOPC1 injection

Exclusion Criteria

SCI due to penetrating trauma
Traumatic anatomical transection, laceration, or inadequate decompression of the spinal cord based on prior surgery or MRI
Any concomitant injury that interferes with the performance, interpretation, or validity of neurological examinations, such as multiple spinal cord lesions, brachial/lumbar plexus injury, cauda equina injury or traumatic brain injury
Subjects with a cavity structure that would preclude successful transplantation, as identified on MRI, which may include septations or irregularities in tissue structure
Persons with syringomyelia, defined as those with progressively enlarging cysts on T2-weighted images associated with neurological decline
Inability to communicate effectively with neurological examiner such that the validity of patient data could be compromised
Organ damage or systemic disease that would create an unacceptable risk for surgery or immunosuppression
Need for mechanical support of ventilation (ventilator, continuous positive airway pressure \[CPAP\], bi-level positive airway pressure \[BiPAP\]), excluding supplemental oxygen, at baseline
History of any malignancy (except non-melanoma skin cancers). For cancers in remission for more than five years, enrollment is allowed with concurred documented approval of principal investigator, oncologist, and Sponsor's medical monitor prior to enrollment
Pregnant or nursing women
Subjects with an implanted spinal cord stimulator (SCS), whether temporary or permanent.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Downey?

Yes, this clinical trial (NCT06841770) has an active research site in Downey, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Spinal Cord Injury Cervical Treatment Options in Downey, CA

If you're searching for spinal cord injury cervical treatment options in Downey, CA, this clinical trial (NCT06841770) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Downey research site is actively enrolling participants for this clinical trial. You'll receive care from experienced spinal cord injury cervical specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all spinal cord injury cervical clinical trials near you to find additional studies recruiting in your area.

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