Louisville, KYNCT07504055Now EnrollingIRB Ready

Spinal Cord Injury Clinical Trial in Louisville, KY

Access cutting-edge spinal cord injury treatment through this clinical trial at a research site in Louisville. Study-provided care at no cost to qualified participants.

Sponsored by University of Louisville

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Expert Care in Louisville

Access spinal cord injury specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related spinal cord injury treatment provided free

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Check if you qualify for this spinal cord injury clinical trial in Louisville, KY

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Why Participate?

  • No-Cost Study Care

  • Local to Louisville

    Convenient for KY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Louisville site if eligible
  4. 4Begin participation

About This Spinal Cord Injury Study in Louisville

The goal of this clinical trial is to learn if non-invasive spinal cord stimulation intervention improves blood pressure regulation in individuals with chronic spinal cord injury. The main questions it aims to answer are: * Can site specific spinal cord stimulation enhance blood pressure regulation? * Does this stimulation affect enzymes responsible for blood pressure regulation? Researchers will stimulate different sites of spinal cord and compare to see if site-specific stimulation provide blood pressure stability. Participants will have up to six pairs of self-adhesive conductive electrodes placed on the skin over the spinal cord (midline and/or just to the left and right of midline) as cathodes and up to six pairs of self-adhesive electrodes located symmetrically on the skin over the iliac crests, clavicles, shoulders, and/or abdominal muscles (left and right of the umbilicus) as anodes for stimulation of the spinal cord.

Sponsor: University of Louisville

Who Can Participate

Inclusion Criteria

At least 18 years old,
Stable medical condition,
Non-progression SCI (no negative change in the neurological level and motor-completeness assess during screening when compared to the neurological status assessed at 6-month period after injury or at least 6 months prior to the screening),
Motor-complete SCI according to the American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade "A," "B," or "C" above T1 spinal level according to the ASIA International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) Neurological Level of Injury (NLI),
Sustained SCI at least 12 months prior to entering the study,
Evidence of symptomatic hypotension as determined by a total score \>0 on the Orthostatic Hypotension Symptom Assessment (OSHA),
Normal renal function as defined by eGFR \> 59 ml/min/1.73, creatinine value within the range of 0.6-1.2 mg/dl, and BUN values within the range of 7-18 mg/dl,
Competent to give informed consent for the research protocol,
Able to understand instructions.

Exclusion Criteria

Major pulmonary or cardiovascular disease unrelated to SCI,
Ventilator dependence,
Painful musculoskeletal dysfunction that might interfere with testing or stimulation,
Unhealed fracture that might interfere with testing or stimulation,
Unhealed contracture that might interfere with testing or stimulation,
Unhealed pressure sore that might interfere with testing or stimulation,
Untreated clinically significant depression or psychiatric disorders,
Ongoing drug abuse,
Malignancy ,
Class III obesity (BMI \>40) and at least one co-morbidity thereof: a) Type 2 diabetes as defined by ≥6.5% level on two separate glycated hemoglobin (A1C) tests, b) hypertension as defined by consistent blood pressure readings of ≥140/90 mmHg or taking medication for blood pressure,
Acute or chronic obstructive deep vein thrombosis,
Secondary hypotension unrelated to SCI (anemia, hypervolemia, endocrine and neurological diseases),
Major esophageal/gastrointestinal problem,
Currently pregnant (females of childbearing potential only),
Other major medical illness contraindicated for testing or stimulation.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Louisville?

Yes, this clinical trial (NCT07504055) has an active research site in Louisville, KY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Spinal Cord Injury Treatment Options in Louisville, KY

If you're searching for spinal cord injury treatment options in Louisville, KY, this clinical trial (NCT07504055) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Louisville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced spinal cord injury specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all spinal cord injury clinical trials near you to find additional studies recruiting in your area.

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