Durham, NCNCT05786417Now EnrollingIRB Ready

Stable Angina Clinical Trial in Durham, NC

Access cutting-edge stable angina treatment through this phase 4 clinical trial at a research site in Durham. Study-provided care at no cost to qualified participants.

Sponsored by Yale University

Quick Self-Assessment

See if you qualify for this Durham location

Preparing your pre-screening questions…

Expert Care in Durham

Access stable angina specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related stable angina treatment provided free

Apply for This Durham Location

Check if you qualify for this stable angina clinical trial in Durham, NC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Durham

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Durham site if eligible
  4. 4Begin participation

About This Stable Angina Study in Durham

To establish the effectiveness and tolerability of standard of care anti-anginal treatment (beta-blocker and calcium channel blocker medications) in older adults with symptomatic Stable Ischemic Heart Disease (SIHD) and multiple chronic conditions (MCC).

Sponsor: Yale University

Who Can Participate

Inclusion Criteria

OLDER ADULTS WITH SIHD AND MCC
Age ≥65 years
≥ 2 Multiple Chronic Conditions as defined by Centers for Medicare and Medicaid Services (CMS)
Diagnosis of Symptomatic Stable Ischemic Heart Disease with plans to initiate medical therapy identified by at least one of the following:
positive non-invasive functional or anatomic testing suggestive of obstructive coronary artery disease
coronary angiography with stenosis ≥70% in a coronary artery ≥2 mm in diameter or ≥50% stenosis of left main
Invasive coronary angiography with positive physiologic testing in at least one vessel (FFR ≤ 0.80 or iFR ≤0.89) CAREGIVERS
Age ≥ 18 years
Identified as caregiver of LIVEBETTER participant

Exclusion Criteria

OLDER ADULTS WITH SIHD AND MCC
Current taking (both) a beta-blocker AND a calcium channel blocker\
Contraindication to beta-blockers or calcium channel blockers including:
significant hypotension
high grade AV block
severe symptomatic bradycardia
severe obstructive lung disease
Documented intolerance to beta-blockers or calcium channel blockers
Probable or definite high-risk coronary artery disease including unrevascularized left main disease and/or unrevascularized multi-vessel disease including the proximal left anterior descending (LAD) artery with plans for immediate complete revascularization
Plans for complete revascularization within 2 weeks
Clear clinical indication for beta-blockers or calcium channel blockers that precludes dose adjustment or crossover:
Diagnosis of acute coronary syndrome (ACS) with reduced ejection fraction within past year
Heart failure with reduced ejection fraction (HFrEF) within past year
Actively participating in another clinical trial involving an investigational medication or device
Primary language other than English or Spanish
Inability to complete follow-up (e.g. life expectancy \<12 months, impaired decision-making determined by validated instrument)
Previously enrolled in LIVEBETTER
Refused informed consent CAREGIVERS
Professional caregiver (i.e. not a relative or close friend of the participant)
Primary language other than English or Spanish
Inability to complete follow-up
Previously enrolled in LIVEBETTER
Refused informed consent

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Durham?

Yes, this clinical trial (NCT05786417) has an active research site in Durham, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stable Angina Treatment Options in Durham, NC

If you're searching for stable angina treatment options in Durham, NC, this clinical trial (NCT05786417) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Durham research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced stable angina specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Ready to Join in Durham?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Durham, NC