Birmingham, ALNCT07146516Now EnrollingIRB Ready

Stickler Syndrome Type 1 Clinical Trial in Birmingham, AL

Access cutting-edge stickler syndrome type 1 treatment through this clinical trial at a research site in Birmingham. Study-provided care at no cost to qualified participants.

Sponsored by Helen Keller Eye Research Foundation

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Expert Care in Birmingham

Access stickler syndrome type 1 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related stickler syndrome type 1 treatment provided free

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Check if you qualify for this stickler syndrome type 1 clinical trial in Birmingham, AL

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Why Participate?

  • No-Cost Study Care

  • Local to Birmingham

    Convenient for AL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Birmingham site if eligible
  4. 4Begin participation

About This Stickler Syndrome Type 1 Study in Birmingham

The goal of this clinical trial is to prospectively document to what extent the OSC/SS prophylactic laser retinopexy procedure works to prevent retinal detachment in SS in children and adults. Researchers will compare the OSC/SS procedure in SS to the natural progression of SS to see to what extent the OSC/SS procedure works to prevent retinal detachment. Participants will: * Have the OSC/SS procedure in one or both eyes * Have eye tests * Have genetic testing for SS as needed * Visit the study center 9 times over 5 years for checkups and tests * Have data for the untreated fellow-eye collected and used as study data if available

Sponsor: Helen Keller Eye Research Foundation

Who Can Participate

Inclusion Criteria

No contraindications to laser retinopexy surgery per local site criteria.
Capable of giving signed informed consent, and assent (as appropriate)
Signature of research informed consent form from participant, or participant's legally authorized representative (LAR)/parent(s)/legal guardian
Male or female of any age
SS type 1 or type 2 confirmed by genetic testing

Exclusion Criteria

Presence of media opacity (for example, dense cataract, corneal scar) or poor pupillary dilation that precludes adequate OSC/SS performance, laser treatment, or imaging.
Prior prophylactic laser treatment that cannot be supplemented to achieve a complete OSC/SS pattern or exceeds the designated OSC/SS pattern.
RD in the eye to be treated.
Significant intraocular hemorrhage in the eye to be treated.
Uncontrolled ocular conditions (e.g., glaucoma) that may be worsened by the procedure or preclude follow-up.
Any other ocular condition that precludes the ability to perform adequate laser treatment under scleral depression.
Any systemic medical contraindication where the risk of intervention outweighs the potential benefit.
Known pathogenic mutations in genes associated with other inherited retinal detachment syndromes, including but not limited to: FEVR-related genes: FZD4, LRP5, TSPAN12, NDPX-linked retinoschisis (RS1) Wagner Syndrome (VCAN).
Other syndromes associated with increased risk of retinal detachment (for example, Knobloch syndrome, Marfan syndrome, Pierson syndrome).
History of Coats disease.
History of Retinopathy of Prematurity (with or without laser treatment).
Prior laser photocoagulation in the study eye for any indication other than the following: retinal detachment prophylaxis for Stickler syndrome, treatment of lattice degeneration, or treatment of retinal tears.
Laser photocoagulation, for the indications permitted in exclusion criteria 12, that cannot be supplemented to meet the OSC/SS criteria.
Previous cryopexy.
Previous scleral buckle.
Previous vitrectomy in the study eye for any reason.
Significant peripheral retinal pathology unrelated to Stickler that increases the risk of retinal detachment including but not limited to: retinoschisis, hemorrhages, angiomatous lesions, pars planitis.
History of ocular trauma with significant trauma to the posterior segment of the eye and may increase the risk of retinal detachment including Ruptured globe, Vitreous hemorrhage, Commotio retinae, Traumatic macular hole, Intraocular foreign body.
Inability or unwillingness to comply with required follow-up schedule (clinical visits, imaging).
Anticipated relocation, foster care instability, or any factor significantly limiting longitudinal follow-up.
Investigator judgment: Any condition not listed above that could interfere with the trial's integrity or subject safety.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Birmingham?

Yes, this clinical trial (NCT07146516) has an active research site in Birmingham, AL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stickler Syndrome Type 1 Treatment Options in Birmingham, AL

If you're searching for stickler syndrome type 1 treatment options in Birmingham, AL, this clinical trial (NCT07146516) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Birmingham research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stickler syndrome type 1 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stickler syndrome type 1 clinical trials near you to find additional studies recruiting in your area.

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