Seattle, WANCT05591196Now EnrollingIRB Ready

Stroke, Ischemic Clinical Trial in Seattle, WA

Access cutting-edge stroke, ischemic treatment through this clinical trial at a research site in Seattle. Study-provided care at no cost to qualified participants.

Sponsored by University of Washington

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Expert Care in Seattle

Access stroke, ischemic specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related stroke, ischemic treatment provided free

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Check if you qualify for this stroke, ischemic clinical trial in Seattle, WA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Seattle

    Convenient for WA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Seattle site if eligible
  4. 4Begin participation

About This Stroke, Ischemic Study in Seattle

The recovery from a stroke is often incomplete. It is the leading cause of acquired permanent disability in the adult population. Persistent functional loss of the hand and arm contributes significantly to disability. However, the current standard of care to treat hand and arm movements are inadequate. There is an urgent need for innovative and effective therapies for recovery of the upper limb after stroke. Growing evidence shows that electrical spinal cord stimulation, combined with activity-dependent rehabilitation, enables voluntary movement of paralyzed muscles in some neurologic disorders, such as spinal cord injury. The investigators hypothesize that spinal networks that lost control after stroke can be activated by non-invasive electrical stimulation of the spinal cord to improve functional recovery. The aims of the study are: 1. to determine the improvements in hand and arm function that result from the combined application of non-invasive spinal stimulation and activity-based rehabilitation. Surface electrodes placed over the skin of the neck will be used for non-invasive electrical stimulation of the spinal cord. Functional task practice will be used for activity-dependent rehabilitation, 2. to evaluate long-lasting benefits to hand and arm function that persist beyond the period of spinal stimulation.

Sponsor: University of Washington

Who Can Participate

Inclusion Criteria

Radiologically documented single ischemic stroke resulted in hemiplegia/hemiparesis
At least six months post-stroke
Upper Extremity Fugl-Meyer Assessment score "moderate" or "moderate-mild" (29-53 inclusive out of 66) at the screening visit
Medically and neurologically stable, as determined by medical history and documented physical examination
For women of childbearing potential, a negative over-the-counter pregnancy test at study entry and willingness to practice adequate contraception during the study
Ability to attend sessions three times per week
Adequate social support to participate in all intervention and baseline, follow-up assessment sessions throughout eight months.
Ability to read, comprehend and speak English

Exclusion Criteria

Hemorrhagic stroke
History of multiple strokes
Active implanted stimulator (e.g., pacemaker, vagus nerve stimulator, cochlear implant, etc.) or baclofen pump
Aphasia or any other deficit in communication that interferes with reasonable study participation
Moderate to severe cognitive impairment
Presence of neglect (inability to perceive or awareness of, or loss of attention to the weaker half of the body)
Severe spasticity in the upper limb
Taking baclofen more than 30 mg/day
Change in baclofen dose within four weeks before enrollment
Receiving benzodiazepines, dantrolene, tizanidine, anticoagulant, or antiepileptic medication
Botulinum toxin injection to the upper limb muscles within six months before enrollment
Severe joint contractures in the affected hand and arm
History of spontaneous seizure that had occurred one month or longer after the stroke

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Seattle?

Yes, this clinical trial (NCT05591196) has an active research site in Seattle, WA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stroke, Ischemic Treatment Options in Seattle, WA

If you're searching for stroke, ischemic treatment options in Seattle, WA, this clinical trial (NCT05591196) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Seattle research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stroke, ischemic specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stroke, ischemic clinical trials near you to find additional studies recruiting in your area.

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