NCT05425615 · Medical College of Wisconsin
Language Processing and TMS
What this study is about
This study will examine the effect of TMS on people with stroke and aphasia as well as healthy individuals.
View original scientific description
This study will examine the effect of TMS on people with stroke and aphasia as well as healthy individuals.
Interventions
DEVICE
Transcranial Magnetic Stimulation
Deymed DuoMag XT-100 rTMS
Primary outcome measures
Reaction time on language task performance
Time frame: Language tasks administered immediately before and/or after TMS administration (same day).
Improvement on language task performance as measured by decrease in reaction time.
Accuracy on language task performance
Time frame: Language tasks administered immediately before and/or after TMS administration (same day).
Improvement on language task performance as measured by increase in accuracy.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Diagnosed with left hemisphere stroke
- Consent date \>= 1 month after stroke onset
- Right-handed
- Fluent in English
- 18 years of age or older
Exclusion criteria
- Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
- Non-decisional per decisionality questionnaire or other clinical assessment
- Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)
- A chronic medical condition that is not treated or is unstable
- Presence of
- cardiac stimulators or pacemakers or intracardiac lines
- neurostimulators
- medication infusion device
- any other implants near the scalp (e.g., cochlear implants) or in the eye
- metal in the body
- History of skull fractures, or skin diseases
- History of ongoing or unmanaged seizures or a family history of epilepsy
- Presence of factors that potentially decrease seizure thresholds
- On pro-convulsant medications
- Untreated Sleep deprivation or insomnia
- Ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)
- History of dyslexia or other developmental learning disabilities
Where
- Milwaukee, Wisconsin
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 11, 2025 · Source of record for eligibility and locations