NCT02359812 · University of Maryland, Baltimore
Robot Aided Rehabilitation - Multi-joint Evaluations
(Aim1)
What this study is about
Sensory and motor impairments following stroke can lead to substantial disability involving the treatment group$1 and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and proprioceptive acuity will be present among multiple degree of freedom in the upper limb. The stiffness and spasticity will increase with time post-stroke.
View original scientific description
Sensory and motor impairments following stroke can lead to substantial disability involving the arm and hand. The investigator hypothesized that excessive local and cross-coupled stiffness, diminished individuation and proprioceptive acuity will be present among multiple degree of freedom in the upper limb. The stiffness and spasticity will increase with time post-stroke. The objective of this study is to quantify the progression throughout the arm and hand during recovery from stroke. The investigator will measure the clinical assessment scores, and neuromechanical properties including range of motion, active and passive cross coupling, and spasticity by the IntelliArm robot.
Primary outcome measures
Changes from baseline Graded Wolf Motor Function Test (WMFT) at six time points
Time frame: 2 week (baseline), 1 month, 2 month, 3 month, 4 month, 5 month and 6 month post stroke
The WMFT is a quantitative measure of upper extremity motor ability through timed and functional tasks.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- First focal unilateral lesion, ischemic or hemorrhagic
- Had a stroke less than a month prior to enrollment
- Rated between stages 1-4 on the Chedoke McMaster Stroke Assessment Impairment Inventory: Stage of Recovery of the Arm
- Rated between stages 1-4 on the Chedoke McMaster Stroke Assessment Impairment Inventory: Stage of Recovery of the Hand
Exclusion criteria
- Other unrelated or musculoskeletal injuries
- Unable to sit in a chair for 3 consecutive hours
- Score of less than 22 on the Mini Mental Status Exam
- Poor fit into equipment used in study which compromises proper use. This will be determined by the judgment of study staff
Where
- Baltimore, Maryland
Collaborators
National Institute on Disability, Independent Living, and Rehabilitation Research, North Carolina State University
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Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
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How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 9, 2025 · Source of record for eligibility and locations