Cleveland, OHNCT05866003Now EnrollingIRB Ready

Stroke Clinical Trial in Cleveland, OH

Access cutting-edge stroke treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by MetroHealth Medical Center

Quick Self-Assessment

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Expert Care in Cleveland

Access stroke specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related stroke treatment provided free

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Check if you qualify for this stroke clinical trial in Cleveland, OH

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Stroke Study in Cleveland

After a stroke, it is very common to lose the ability to open the affected hand. Occupational and physical rehabilitation therapy (OT and PT) combined with non-invasive brain stimulation may help a person recover hand movement. The purpose of this study is to compare 3 non-invasive brain stimulation protocols combined with therapy to see if they result in different amounts of recovery of hand movement after a stroke.

Sponsor: MetroHealth Medical Center

Who Can Participate

Inclusion Criteria

Age ≥ 21 and ≤ 90
≥ 6 and ≤ 24 months since first clinical hemorrhagic or nonhemorrhagic stroke
Able to follow 3-stage command
Able to remember 2 of 3 items after 30 minutes
Full volitional elbow extension/flexion and hand opening/closing of unaffected limb
Adequate active movement of shoulder and elbow to position the paretic hand in the workspace for table-top task practice
Patient must be able to sit unassisted in an armless straight-back chair for the duration of the screening portion of the eligibility assessment
Medically stable
≥ 10° finger and wrist extension
Skin intact on hemiparetic arm, hand and scalp
Muscle contraction can be elicited with Transcranial Magnetic Stimulation
Unilateral upper limb hemiparesis with finger extensor strength of ≤ grade 4/5 on the Medical Research Council (MRC) scale
Score of ≥1/14 and ≤ 11/14 on the hand section of the upper extremity Fugl-Meyer Assessment
While relaxed, surface NMES of finger extensors and thumb extensors and/or abductors produces a functional degree of hand opening without pain.

Exclusion Criteria

Co-existing neurological condition other than prior stroke involving the hemiparetic upper limb (e.g., peripheral nerve injury, PD, SCI, TBI, MS).
Uncontrolled seizure disorder
Use of seizure lowering threshold medications and the discretion of the study physician
Cardiac pacemaker or other implanted electronic device
IM Botox injections in any UE muscle in the last 3 months
Insensate arm, forearm, or hand
Deficits in communication that interfere with reasonable study participation
Severely impaired cognition and communication
Uncompensated hemi-neglect (extinguishing to double simultaneous stimulation)
Severe shoulder or hand pain (unable to position hand in the workspace without pain)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT05866003) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stroke Treatment Options in Cleveland, OH

If you're searching for stroke treatment options in Cleveland, OH, this clinical trial (NCT05866003) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stroke clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Cleveland, OH