Is NCT06268041 recruiting in Cincinnati, OH?

Yes, NCT06268041 is currently recruiting participants at its Cincinnati, OH location. This stroke clinical trial is actively enrolling qualified participants.

How do I join the stroke clinical trial in Cincinnati?

To join this clinical trial in Cincinnati, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Cincinnati clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Stroke Clinical Trial in Cincinnati, OH

About This Stroke Study in Cincinnati

People who had a stroke at least 6 months prior and who still have difficulty with walking will each be randomly assigned to receive either moderate or vigorous intensity walking exercise. Both protocols will be performed individually with a physical therapist for 45 minutes, 3x/week for 12 weeks. Measures including walking function will be assessed at baseline (PRE), after 4, 8 and 12 weeks of training (12WK) and at 3-month follow up (3moPOST), by raters who are unaware of the participant randomization.

Sponsor: University of Cincinnati

Who Can Participate

Inclusion Criteria

Age 30-85 years at time of consenting

Hemiparesis from ischemic and/or hemorrhagic strokes

Most recent stroke for which participant sought treatment, at least 6 months prior to study consent

Walking speed \<1.0 m/s on the 10-meter walk test

Able to walk 10m over ground with assistive devices as needed and no continuous physical assistance from another person (guarding and intermittent assistance for loss of balance allowed)

Able to walk at least 3 minutes on the treadmill at ≥0.13m/s (0.3 mph)

Stable cardiovascular condition (AHA class B, allowing for aerobic capacity \<6 metabolic equivalents)

Able to communicate with investigators, follow a 2-step command and correctly answer consent comprehension questions

Exclusion Criteria

Exercise testing uninterpretable for ischemia or arrhythmia (e.g. resting ECG abnormality that makes exercise ECG uninterpretable for ischemia and no other clinical testing from the past year available to rule out these conditions)

Evidence of significant arrhythmia or myocardial ischemia on treadmill ECG graded exercise test in the absence of recent (past year) more definitive clinical testing (e.g. stress nuclear imaging) with negative result

Hospitalization for cardiac or pulmonary disease within past 3 months

Implanted pacemaker or defibrillator with an upper heart rate limit that would interfere with exercise testing or prescription, or with unknown limit

Significant ataxia or neglect (score of 2 on NIH stroke scale item 7 or 11)

Severe lower limb spasticity (Ashworth \>2)

Known recent history (\<3 months) of unstable substance abuse or unstable mental illness

Major post-stroke depression (Patient Health Questionnaire \[PHQ-9\] ≥ 10) in the absence of depression management by a health care provider

Currently participating in physical therapy or another interventional study targeting walking function

Recent (\<2 weeks) or planned changes in lower limb orthotic or spasticity management

Foot drop or lower limb joint instability without adequate stabilizing device, as assessed by a physical therapist

Clinically significant neurologic disorder other than stroke or unable to walk outside the home prior to stroke

Unable to walk outside the home prior to stroke

Other significant medical condition likely to limit improvement or jeopardize safety as assessed by a physical therapist (e.g. joint contracture, gait limited by pain)

Previous exposure to fast treadmill walking (\>3 cumulative hours) in the past year

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cincinnati?

Yes, this clinical trial (NCT06268041) has an active research site in Cincinnati, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stroke Treatment Options in Cincinnati, OH

If you're searching for stroke treatment options in Cincinnati, OH, this clinical trial (NCT06268041) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cincinnati research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stroke clinical trials near you to find additional studies recruiting in your area.

Stroke Clinical Trial in Cincinnati, OH

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