Charleston, SCNCT04877444Now EnrollingIRB Ready

Stroke Clinical Trial in Charleston, SC

Access cutting-edge stroke treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by VA Office of Research and Development

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in Charleston

Access stroke specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related stroke treatment provided free

Apply for This Charleston Location

Check if you qualify for this stroke clinical trial in Charleston, SC

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Stroke Study in Charleston

Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persistent physical and mental difficulties such as reduced physical and cognitive function and depression. Developing innovative treatments that address these problems is necessary to improve long-term outcomes for stroke survivors. Aerobic exercise (AEx) can improve physical and cognitive function, and reduce depression. Additionally, AEx may enhance physical rehabilitation by making the brain more receptive to, and consequently improving the response to an intervention. Therefore, combining AEx with physical rehabilitation has the potential to improve multiple aspects of stroke recovery. This study will examine the effect of combining AEx with physical rehabilitation on physical and mental function in stroke survivors. By gaining a better understanding of the effects of this combined intervention the investigators aim to advance the rehabilitative care of Veteran stroke survivors.

Sponsor: VA Office of Research and Development

Who Can Participate

Inclusion Criteria

experienced unilateral stroke at least 6 months prior;
voluntarily shoulder flexion of the affected arm 20 degrees with simultaneous elbow extension 10 degrees;
moderate arm movement impairment (UE Fugl-Meyer Assessment \> 21 but \< 52 points;
passive range of motion in paretic shoulder, elbow, wrist, thumb and fingers within 20 degrees of normal;
50-90 years of age;
ability to communicate as per the therapists' judgement at baseline testing;
ability to complete and pass an exercise tolerance test; 8) Box \& Block test score of at least 3 blocks in 60 seconds with the affected arm.

Exclusion Criteria

lesion in brainstem/cerebellum as these may interfere with visual-perceptual/cognitive skills needed for motor re-learning;
presence of other neurological disease that may impair motor learning skills;
orthopedic condition or impaired corrected vision that alters reaching ability (e.g., prior rotator cuff tear without full recovery);
paretic arm pain that interferes with reaching;
unable to understand or follow 3-step directions;
severe cognitive impairment (MoCA score 17);
severe aphasia;
inability to read English,
history of congestive heart failure, unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's;
Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest;
History of COPD or oxygen dependence;
History of DVT or pulmonary embolism within 6 months;
Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions;
UBACC score \< 15; and for brain stimulation procedures only:
electronic or metallic implants;
history of seizures;
women of child bearing potential.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT04877444) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stroke Treatment Options in Charleston, SC

If you're searching for stroke treatment options in Charleston, SC, this clinical trial (NCT04877444) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stroke clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC