Is NCT06682429 recruiting in Irvine, CA?

Yes, NCT06682429 is currently recruiting participants at its Irvine, CA location. This stroke clinical trial is actively enrolling qualified participants.

How do I join the stroke clinical trial in Irvine?

To join this clinical trial in Irvine, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Irvine clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Stroke Clinical Trial in Irvine, CA

About This Stroke Study in Irvine

The purpose of this research study is to evaluate whether telerehabilitation targeting arm movement, when added to usual care, improves arm function and reduces global disability after stroke, compared to usual care alone. Patients with arm weakness due to stroke that happened in the past 90-150 days will be randomized into one of two groups: \[1\] TR and usual care; \[2\] usual care only (no TR), but people in the usual care group will be offered TR once the study is done. TR consists of 70 minutes/day of activities targeting arm function, 6 days a week for 6 weeks.

Sponsor: University of California, Los Angeles

Who Can Participate

Inclusion Criteria

Age 18-80 years at the time of randomization

The index stroke was radiologically verified, due to ischemia or intracerebral hemorrhage (ICH), and had time of onset 120±30 days prior to randomization

The stroke caused upper extremity deficits as defined by Action Research Arm Test score 18-44 (out of 57) at Baseline Visit 1

Box \& Block Test score with affected arm is ≥1 block in 60 seconds at Baseline Visit 1

Able to successfully perform all 3 rehabilitation exercise test examples (simple commands) at Baseline Visit 1

Informed consent and behavioral contract signed by the subject (i.e., no surrogate consent)

Exclusion Criteria

A major, active, coexistent neurological, psychiatric, or medical disease that reduces the likelihood that a subject will be able to comply with all study procedures

Unable or unwilling to perform study procedures/therapy, or expectation of noncompliance with study procedures/therapy, or expectation that subject cannot participate in all study visits

A diagnosis (apart from the index stroke) that substantially affects paretic arm function

Severe depression, defined as Geriatric Depression Scale Score \>10/15 at Baseline Visit 1

Significant cognitive impairment, defined as Montreal Cognitive Assessment score \<22 \[a lower score is permitted if due to aphasia and allowed by the site PI\]

Deficits in communication that interfere with reasonable study participation

Severe UE spasticity, defined as presence of contracture or modified Ashworth Scale score=4 in either biceps or pectoralis

Modified Rankin Scale score was \>2 prior to the index stroke

A new symptomatic stroke has occurred since the index stroke, or a separate stroke occurred within 30 days prior to the index stroke

Lacking visual acuity, with or without corrective lens, of 20/50 or better in at least one eye

Life expectancy \< 9 months

Pregnant; women of child-bearing potential must have a negative pregnancy test

Botulinum toxin to the paretic arm: received in the prior 3 months OR expected by the 8-Month Visit

Concurrent enrollment in another therapy-based investigational study where the duration of the investigational therapy's activity is likely to occur during the subject's participation in the study

Subject lacks sufficient English or Spanish to comply with study procedures and TR instructions

Expectation that subject will not have a single domicile address during the 6 weeks of therapy that is within 1.5-hr drive of the central study site \[this can be waived at the discretion of the site PI\]

Contraindication to MRI

On isolation precautions, e.g., due to active COVID-19

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Irvine?

Yes, this clinical trial (NCT06682429) has an active research site in Irvine, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Stroke Treatment Options in Irvine, CA

If you're searching for stroke treatment options in Irvine, CA, this clinical trial (NCT06682429) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Irvine research site is actively enrolling participants for this clinical trial. You'll receive care from experienced stroke specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all stroke clinical trials near you to find additional studies recruiting in your area.

Stroke Clinical Trial in Irvine, CA

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