NCT06375083 · VA Eastern Colorado Health Care System
Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression
What this study is about
This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.
View original scientific description
This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.
Interventions
BEHAVIORAL
c-CBT for Suicide Prevention
Online c-CBT for SP The computerized Cognitive Behavioral Therapy for Suicide Prevention (cCBT-SP) course is comprised of 12 online sessions and is augmented by use of a companion workbook.
BEHAVIORAL
c-CBT or Depression
The computerized Cognitive Behavioral Therapy for Depression (cCBT-D) course is comprised of 12 online sessions and is augmented by use of a companion workbook.
Primary outcome measures
Client Satisfaction Questionnaire
Time frame: 12 weeks
Acceptability
Internet Evaluation and Utility Questionnaire
Time frame: 12 weeks
Acceptability
Internet Impact and Effectiveness Questionnaire
Time frame: 12 weeks
Acceptability
Narrative Evaluation of Intervention Interview
Time frame: 12 weeks
Acceptability
Recruitment Rate
Time frame: 12 weeks
Number of individuals who consented to participate
Completion of intervention
Time frame: 12 weeks
Number of participants who completed most or all of the sessions
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Veterans between the ages of 18 and 65
- Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA Care
- Recent suicidal ideation (past month; C-SSRS Screener -Yes to Item 2) and history of lifetime suicidal behavior (lifetime, C-SSRS Screener - Yes to Item 6)
- Reliable access to a computer/tablet and the internet
- Ability to provide informed consent
Exclusion criteria
- Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
- Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
- Severe cognitive impairment, as determined by screening or electronic medical record
- Currently enrolled in/participating in another mental health-related intervention research study Cohort B - cCBT-D Program Inclusion Criteria:
- Veterans between the ages of 18 and 65
- Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA care
- Mild to moderate depressive symptoms, as determined by the PHQ-9, (score of 5-14)
- Reliable access to a computer/tablet and the internet
- Ability to provide informed consent Exclusion Criteria:
- PHQ-9 score below 4 or 15 and above
- Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
- Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
- Severe cognitive impairment, as determined by screening or electronic medical record
- Currently enrolled in/participating in other intervention research study
Where
- Aurora, Colorado
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 19, 2026 · Source of record for eligibility and locations