Memphis, TNNCT07191119Now EnrollingIRB Ready

Survivor of Childhood Cancer Clinical Trial in Memphis, TN

Access cutting-edge survivor of childhood cancer treatment through this clinical trial at a research site in Memphis. Study-provided care at no cost to qualified participants.

Sponsored by St. Jude Children's Research Hospital

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Expert Care in Memphis

Access survivor of childhood cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related survivor of childhood cancer treatment provided free

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Check if you qualify for this survivor of childhood cancer clinical trial in Memphis, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Memphis

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Memphis site if eligible
  4. 4Begin participation

About This Survivor of Childhood Cancer Study in Memphis

This pilot study will assess the usefulness and potential effectiveness of using transcutaneous auricular vagus nerve stimulation (tVNS) for treating insomnia in adult survivors of childhood acute lymphoblastic leukemia (ALL). Participants will be randomized to receive either active (verum) or inactive (sham) nightly stimulation using a non-invasive earbud device over two time periods: 2 weeks and 8 weeks. The study will assess adherence to the intervention and estimate its effects on sleep quality, stress, and neurocognitive function. Primary Objective: Aim 1: To determine a) short-term and b) long-term feasibility of tVNS in terms of participation in ALL Survivors with moderate to severe insomnia. Aim 2: To estimate the effect size of tVNS on sleep quality, stress, and neurocognitive outcomes in ALL survivors with insomnia. Exploratory Objectives Aim 1: To investigate the onset of tVNS effect via actigraphy measures over the intervention epoch. Aim 2: To estimate the effect size of genetic variants on sleep quality within verum tVNS.

Sponsor: St. Jude Children's Research Hospital

Who Can Participate

Inclusion Criteria

Survivor of Acute Lymphoblastic Leukemia (ALL)
Enrolled on SJLIFE
Participant was less than 21 years of age at time of diagnosis.
Age 20-50 years at the time of enrollment
Insomnia Severity Index \>=8 (Proxy \>=8) confirmed prior to enrollment
Access to home Wi-Fi and Smartphone
Participant is able to speak and understand the English language
Participant is able and willing to give consent

Exclusion Criteria

Unable to understand the details and requirements of the study (at the discretion of the PI)
Female participants who are pregnant or planning to become pregnant
Presence of implanted electrical medical devices (i.e. pacemaker)
Currently taking medication intended to treat neurocognitive impairment (i.e. stimulants) or medications prescribed for seizure management
History of skin irritation or other issues during stimulation of inner ear
Currently utilizing a technological intervention for a sleep disorder (e.g. CPAP)
Medications and behavioral practices (white noise, night-time yoga, etc) are acceptable as long as the insomnia is persistent.
History of a contraindicated health condition including:
Syncope (CTCAE \>2)
Cardiac dysrhythmia (CTCAE \>2)
Vascular Disease (CTCAE \>2)
Coronary Artery Disease (CTCAE \>2)
Active contraindicated heath condition including:
Cranial Nerve Disorder (CTCAE \>2)
Neuropathy (Cranial Nerves) (CTCAE \>2)
Neuralgia (Cranial Nerves) (CTCAE \>2)
Overt Cerebrovascular Accident (CTCAE \>2)
Seizures (Any in most recent 1 year
Currently enrolled or participating in any other neurostimulation or neuromodulation ancillary research studies

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Memphis?

Yes, this clinical trial (NCT07191119) has an active research site in Memphis, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Survivor of Childhood Cancer Treatment Options in Memphis, TN

If you're searching for survivor of childhood cancer treatment options in Memphis, TN, this clinical trial (NCT07191119) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Memphis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced survivor of childhood cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all survivor of childhood cancer clinical trials near you to find additional studies recruiting in your area.

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