Oklahoma City, OKNCT01257269Now EnrollingIRB Ready

Thrombotic Thrombocytopenic Purpura Clinical Trial in Oklahoma City, OK

Access cutting-edge thrombotic thrombocytopenic purpura treatment through this clinical trial at a research site in Oklahoma City. Study-provided care at no cost to qualified participants.

Sponsored by Insel Gruppe AG, University Hospital Bern

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Expert Care in Oklahoma City

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related thrombotic thrombocytopenic purpura treatment provided free

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Check if you qualify for this thrombotic thrombocytopenic purpura clinical trial in Oklahoma City, OK

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Why Participate?

  • No-Cost Study Care

  • Local to Oklahoma City

    Convenient for OK residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Oklahoma City site if eligible
  4. 4Begin participation

About This Thrombotic Thrombocytopenic Purpura Study in Oklahoma City

Hereditary thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) is a rare disorder characterized by thrombocytopenia as a result of platelet consumption, microangiopathic hemolytic anemia, occlusion of the microvasculature with von Willebrand factor-platelet-thrombic and ischemic end organ damage. The underlying patho-mechanism is a severe congenital ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, 13) deficiency which is the result of compound heterozygous or homozygous ADAMTS13 gene mutations. Although considered a monogenic disorder the clinical presentation in Upshaw-Schulman syndrome patients varies considerably without an apparent genotype-phenotype correlation. In 2006 we have initiated a registry for patients with Upshaw-Schulman syndrome and their family members to identify possible triggers of acute bouts of TTP, to document individual clinical courses and treatment requirements as well as possible side effects of long standing plasma substitution, e.g. alloantibody formation or viral infections.

Sponsor: Insel Gruppe AG, University Hospital Bern

Who Can Participate

Inclusion Criteria

Severe ADAMTS13 deficiency ( ≤ 10% activity) and no ADAMTS 13 inhibitor on two or more occasions at least one month apart
Being a family member of a confirmed or suspected patient
Molecular analysis of ADAMTS13 gene with one or more mutations and/or positive infusion trial (full recovered ADAMTS13 activity after infused fresh frozen plasma (FFP) with a plasma half-life of 2-4 days)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Oklahoma City?

Yes, this clinical trial (NCT01257269) has an active research site in Oklahoma City, OK that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Thrombotic Thrombocytopenic Purpura Treatment Options in Oklahoma City, OK

If you're searching for thrombotic thrombocytopenic purpura treatment options in Oklahoma City, OK, this clinical trial (NCT01257269) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Oklahoma City research site is actively enrolling participants for this clinical trial. You'll receive care from experienced thrombotic thrombocytopenic purpura specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all thrombotic thrombocytopenic purpura clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Oklahoma City, OK