NCT03017118 · Massachusetts General Hospital
Turmeric for Patients With Basal Joint Arthritis
What this study is about
The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot randomly assigned Controlled Trial evaluating the impact of turmeric on basal joint arthritis.
View original scientific description
The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- 40 years of age or older
- English fluency and literacy
- Seeking care for basal joint pain
- Tender over basal joint
- Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
- Radiographic evidence of Eaton stage 1 and 2 only
Exclusion criteria
- Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
- Inability or unwillingness to participate in a trial study
- Rheumatoid Arthritis or other inflammatory disorder diagnoses
- Post-traumatic osteoarthritis
- Patients on Coumadin/Steroids/NSAIDs/Tylenol
- Diabetes Mellitus
- Pregnant or lactating women
- Basal joint arthritis of Eaton stage 3
- Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)
Where
- Boston, Massachusetts
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Nov 24, 2025 · Source of record for eligibility and locations