Houston, TXNCT06043362Now EnrollingIRB Ready

Tobacco Dependence Clinical Trial in Houston, TX

Access cutting-edge tobacco dependence treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by Milton S. Hershey Medical Center

Quick Self-Assessment

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Expert Care in Houston

Access tobacco dependence specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related tobacco dependence treatment provided free

Apply for This Houston Location

Check if you qualify for this tobacco dependence clinical trial in Houston, TX

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Tobacco Dependence Study in Houston

The purpose of this clinical trial is to understand the health effects of a new oral nicotine pouch, and also to understand if this product can help reduce traditional cigarette smoking. The main aims are: 1. Understand the impact of nicotine pouch use on toxicant exposure biomarkers, and indicators of potential harms to health. 2. Examine the influence of nicotine pouch use on conventional tobacco product use (cigarettes). Participants will be randomized to one of six nicotine pouch groups (3 nicotine strengths, each with 2 potential flavors) to use over 16 weeks and asked to reduce their cigarette smoking over that time by at least 75% by substituting with the use of the nicotine pouches. Researchers will compare the outcomes of the different nicotine pouch strengths and flavors to each other. Participants will be asked to complete study questionnaires and provide urine, exhaled carbon monoxide, and mouth cell samples, and other health measurements.

Sponsor: Milton S. Hershey Medical Center

Who Can Participate

Inclusion Criteria

Commonly smoke ≥ 5 cigarettes per day (at least 2 days/week) for at least the prior 12 months
Exhaled CO measurement of ≥ 6 parts per million at baseline
Must be interested in reducing cigarette consumption by at least 50% and willing to try nicotine pouches
Able to understand, read and write in English
Access to e-mail and a smartphone/computer that has reliable internet connection
Able to understand and give informed consent

Exclusion Criteria

Plans to quit smoking within the next 30 days
Currently pregnant, breastfeeding, or planning to become pregnant in the next 6 months
Recent (past 3 months) unstable illness that may increase risks of participation or ability to participate fully (e.g. hospitalization for a mental health condition or substance use disorder in prior 6 months, stroke or myocardial infarction in the past year)
Serious current respiratory diseases (e.g. exacerbations of asthma or chronic obstructive pulmonary disease \[COPD\], requiring oxygen or oral prednisone), kidney disease (e.g. requiring dialysis), liver disease (e.g cirrhosis), or any medical disorder/medication that may affect participant safety or biomarker data
Use of a nicotine pouch or other non-cigarette nicotine product (e-cigarette, pipe, cigar, chew, snus, hookah, IQOS) for 5 or more days in the past 28 days
Use of illegal drugs daily or weekly in the past 3 months
Use of combustible (smoked) recreational or medical marijuana weekly in the past 3 months (less frequent smoked medical marijuana or use of other forms of medical marijuana are ok)
Other member of the household currently participating in the study
Any other condition that in the opinion of the investigator would make it unlikely that the participant could comply with the study protocol

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT06043362) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Tobacco Dependence Treatment Options in Houston, TX

If you're searching for tobacco dependence treatment options in Houston, TX, this clinical trial (NCT06043362) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced tobacco dependence specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all tobacco dependence clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Houston, TX