Boston, MANCT04217603Now EnrollingIRB Ready

Tracheobronchomalacia Clinical Trial in Boston, MA

Access cutting-edge tracheobronchomalacia treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Beth Israel Deaconess Medical Center

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Expert Care in Boston

Access tracheobronchomalacia specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related tracheobronchomalacia treatment provided free

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Check if you qualify for this tracheobronchomalacia clinical trial in Boston, MA

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Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Tracheobronchomalacia Study in Boston

The purpose of this protocol is to perform a prospective, randomized, double-blinded, pacebo-controlled clinical trial to determine the influence of a non-invasive positive pressure ventilation device on exercise capacity and symptoms in adult patients with ECAC. Primary outcome will include the total distance traversed by the study subject during a standard 6-minute walk test, and secondary outcomes will include peak flow measurement and symptom reporting before and after the exercise testing. The study will focus on the use of continuous positive airway pressure (CPAP) device. CPAP is FDA-approved for the treatment of various medical conditions, including obstructive sleep apnea and heart failure, but is not FDA-approved for the treatment of ECAC. The study will enroll 32 ambulatory study subjects with confirmed ECAC at the BIDMC, and each study subject will be monitored for up to 3 months.

Sponsor: Beth Israel Deaconess Medical Center

Who Can Participate

Inclusion Criteria

Patient with a diagnosis of ECAC either via bronchoscopy or CT Scan
Age \> 18 years
Patients that will undergo a diagnostic or therapeutic bronchoscopy as part of their standard of care
Patients with a baseline 6 MWT
Patients that have never used CPAP devices in the past

Exclusion Criteria

Patients with poorly-controlled respiratory comorbidities (asthma, COPD, obstructed sleep apnea, GERD, relapsing polychondritis)
No evidence for acute respiratory tract infection, or respiratory tract infection within the prior 3 weeks
Resting bradycardia (\<50 beats/min), frequent multifocal PVCs, complex ventricular arrhythmia, sustained SVT
Dysrhythmia that might pose a risk during exercise or training
Any disease or condition that interferes with completion of initial or follow-up assessments
Subject has co-morbidities that may significantly reduce subject's ability to improve exercise capacity (e.g., severe arthritis, planned knee surgery) or baseline limitation on 6MWT is not due to dyspnea.
Subject has an inability to walk \>140m (150 yd) in 6 minutes
Subject has an inability to tolerate bronchoscopy under moderate sedation or general anesthesia.
Subject has a known sensitivity to drugs required to perform bronchoscopy.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT04217603) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Tracheobronchomalacia Treatment Options in Boston, MA

If you're searching for tracheobronchomalacia treatment options in Boston, MA, this clinical trial (NCT04217603) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced tracheobronchomalacia specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all tracheobronchomalacia clinical trials near you to find additional studies recruiting in your area.

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