Houston, TXNCT06930690Now EnrollingIRB Ready

Ureteral Stent-Related Symptom Clinical Trial in Houston, TX

Access cutting-edge ureteral stent-related symptom treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by The Methodist Hospital Research Institute

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Expert Care in Houston

Access ureteral stent-related symptom specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related ureteral stent-related symptom treatment provided free

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Check if you qualify for this ureteral stent-related symptom clinical trial in Houston, TX

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Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Ureteral Stent-Related Symptom Study in Houston

The purpose of this study to learn if high-dose dexamethasone, a type of long-acting steroid, works to decrease urinary symptoms and pain after ureteroscopy and stent placement for kidney stones. The main question it aims to answer is: 1\) Does high-dose steroid change the quality of life score on day 2 after surgery Researchers will compare high-dose of dexamethasone (20 mg) to a standard dose of dexamethasone (4 mg) to see if a higher dose of the drug will help with urinary symptoms and pain Participants will: 1. randomly receive 20 mg or 4 mg of dexamethasone (20 mg) at the time of surgery 2. fill out a questionnaire day 1 and day 2 after surgery 3. fill out a medication diary for one week after surgery 4. visit the clinic on day 2 after surgery for checkup 5. visit the clinic on day 4-7 after surgery for check up

Sponsor: The Methodist Hospital Research Institute

Who Can Participate

Inclusion Criteria

Age 18-70 years old
Patients who are undergoing unilateral retrograde ureteroscopy (semi-rigid or flexible) with planned ureteral stent placement for treatment of renal/ureteral stones
Patients who can read and understand English
Patients who can follow up post-operatively within 7 days at Houston Methodist Hospital

Exclusion Criteria

Untreated UTI
HbA1c ≥6.5 on preoperative testing
Patients with prior diagnosis of any type of diabetes mellitus
Patients with immunosuppression, including chronic corticosteroid use
Patients with bleeding disorder
Patients with chronic liver disease, cirrhosis, and liver failure.
Patients taking strong CYP3A4 inducers or inhibitors within two weeks of screening
Chronic opioid analgesic use
Congenital renal abnormalities (e.g. pelvic kidney, ureteric duplication) that may impair stent placement
Concurrent genitourinary malignancy
Urinary diversion
Renal transplantation
History of interstitial cystitis/painful bladder syndrome, prostatitis, pelvic pain due to other conditions (e.g. endometriosis)
Neurologic disorder (e.g. spinal cord injury, multiple sclerosis, spina bifida)
Pregnant or breastfeeding
Patients with cognitive impairments or untreated psychiatric illness

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT06930690) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Ureteral Stent-Related Symptom Treatment Options in Houston, TX

If you're searching for ureteral stent-related symptom treatment options in Houston, TX, this clinical trial (NCT06930690) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced ureteral stent-related symptom specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all ureteral stent-related symptom clinical trials near you to find additional studies recruiting in your area.

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