NCT07192887 · Children's Hospital Medical Center, Cincinnati
Thebaine Urine Testing
What this study is about
To develop and validate a urine drug screen to detect thebaine.
View original scientific description
To develop and validate a urine drug screen to detect thebaine.
Primary outcome measures
Validate thebaine urine screen
Time frame: Enrollment to 48 hours after enrollment
Validate a liquid chromatography-tandem mass spectrometry method to detect thebaine in urine
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Male or female
Exclusion criteria
- Allergy to poppy seeds, or any of the related food stuffs used in the study
- Celiac disease or gluten sensitivity
- Ongoing or opioid use in the past 6 months
- History of renal or hepatic disease or dysfunction
- Inability or unwillingness to give repeated urine specimens
- Unwillingness to refrain from eating poppy seed-containing products during the two-day course of the study
- Non-English speakers (due to study materials being in English)
- BMI greater than 30
- Antibiotic use in the previous 2 months
- Recent ingestion of poppy seeds from the previous 7 days
Where
- Cincinnati, Ohio
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Sep 25, 2025 · Source of record for eligibility and locations