Springfield, ILNCT06262516Now EnrollingIRB Ready

Urothelial Carcinoma Clinical Trial in Springfield, IL

Access cutting-edge urothelial carcinoma treatment through this clinical trial at a research site in Springfield. Study-provided care at no cost to qualified participants.

Sponsored by Case Comprehensive Cancer Center

Quick Self-Assessment

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Preparing your pre-screening questions…

Expert Care in Springfield

Access urothelial carcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related urothelial carcinoma treatment provided free

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Check if you qualify for this urothelial carcinoma clinical trial in Springfield, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Springfield

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Springfield site if eligible
  4. 4Begin participation

About This Urothelial Carcinoma Study in Springfield

The goal of this study is to conduct the first randomized-controlled trial to determine the oncologic efficacy of lymph node dissection in participants with upper tract urothelial cell carcinoma. The main questions it aims to answer are: * To determine oncologic outcomes, specifically 2-year recurrence-free survival * To determine other oncologic outcomes including treatment-free, cancer-specific and overall survival * To determine time to recurrence and recurrence patterns * To determine use of adjuvant therapies * To determine perioperative complications Participants will undergo nephroureterectomy with or without lymph node dissection. Researchers will compare these two groups to determine the oncologic efficacy of performing lymph node dissection.

Sponsor: Case Comprehensive Cancer Center

Who Can Participate

Inclusion Criteria

Adults \> 18 years
Diagnosis of UTUC as determined by upper tract biopsy (either low or high grade)
Planned for nephroureterectomy by their urologic surgeon
Disease that is ≤cT4, N0M0. Participants must have complete TNM staging prior to surgery. cT disease can be determined by biopsy of the mass (if biopsy was deep enough) or imaging (CT/MRI). cN and cM stage must be determined by preoperative imaging of the chest, abdomen and pelvis.
No concomitant muscle-invasive bladder cancer
Subjects must have the ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria

Pathologically enlarged lymph nodes suspicious for metastases which would require lymph node dissection regardless of trial (\>cN0)
Presence of distant metastases
Concomitant muscle invasive bladder cancer
The participant is in a reduced general condition or has a life-threatening disease.
The participant has a psychiatric disorder that precludes them from understanding the consent process.
The patient is pregnant

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Springfield?

Yes, this clinical trial (NCT06262516) has an active research site in Springfield, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Urothelial Carcinoma Treatment Options in Springfield, IL

If you're searching for urothelial carcinoma treatment options in Springfield, IL, this clinical trial (NCT06262516) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Springfield research site is actively enrolling participants for this clinical trial. You'll receive care from experienced urothelial carcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all urothelial carcinoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Springfield, IL