Boston, MANCT06387446Now EnrollingIRB Ready

Valve Heart Disease Clinical Trial in Boston, MA

Access cutting-edge valve heart disease treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Boston Children's Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access valve heart disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related valve heart disease treatment provided free

Apply for This Boston Location

Check if you qualify for this valve heart disease clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Valve Heart Disease Study in Boston

Valves will be taken from hearts donated by organ donors, and implanted into patients who need a new heart valve.

Sponsor: Boston Children's Hospital

Who Can Participate

Inclusion Criteria

Patients requiring aortic, pulmonary, mitral or tricuspid valve replacement.
Pediatric patients 30 days or older and \< 18 years, and adult patients 18-50 yrs. o Particularly patients with significant growth potential
Insufficient options are available for valve replacement o Patients at risk of immunogenic bio-prosthetic valve failure
Discussion with patient /family - option for durable valve rather than traditional prosthesis
ABO compatible
Patient and family able to travel to BCH within 48 hour time frame or within our organ procurement organization
Patients that are able to maintain follow-up at BCH during the duration of the study
Patients that are able to provide medical record authorization for 5 year follow-up

Exclusion Criteria

Age \< 30 days
Irreversible multisystem organ failure; or additive effects of the multiple systems affected making transplant survival unlikely
Progressive systemic disease with early mortality (genetic/metabolic, idiopathic, syndromic)
Morbid obesity (BMI\>35)
Diabetes mellitus with evidence of end-organ damage
Severe chromosomal, neurologic or syndromic abnormalities
Immunocompromised condition (DiGeorge, SCID etc.)
Active infection
History of endocarditis
HIV or chronic hepatitis B or C infection
Malignancy within 5 years prior to transplant
Severe renal or liver failure
Inadequate social support for post-transplant management
Recent history of illicit drug, tobacco or alcohol abuse despite trials/assistance to stop behavior
Evidence of large stroke with high risk for hemorrhagic conversion
Heart transplant recipient
Patients that are unable to follow-up during the initial 6 month window
Patients that are unable to provide medical record authorization for 5 years

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT06387446) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Valve Heart Disease Treatment Options in Boston, MA

If you're searching for valve heart disease treatment options in Boston, MA, this clinical trial (NCT06387446) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced valve heart disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all valve heart disease clinical trials near you to find additional studies recruiting in your area.

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