Pasadena, CANCT07419854Now EnrollingIRB Ready

Volume Loss (Soft Tissue Ptosis or Atrophy ) Clinical Trial in Pasadena, CA

Access cutting-edge volume loss (soft tissue ptosis or atrophy ) treatment through this clinical trial at a research site in Pasadena. Study-provided care at no cost to qualified participants.

Sponsored by Kalpna Kay Durairaj, MD, FACS

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Expert Care in Pasadena

Access volume loss (soft tissue ptosis or atrophy ) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related volume loss (soft tissue ptosis or atrophy ) treatment provided free

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Check if you qualify for this volume loss (soft tissue ptosis or atrophy ) clinical trial in Pasadena, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Pasadena

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pasadena site if eligible
  4. 4Begin participation

About This Volume Loss (Soft Tissue Ptosis or Atrophy ) Study in Pasadena

The goal of this clinical trial is to evaluate the potential of Calcium Hydroxylapatite (CaHA) to restore facial volume and improve skin quality in patients with GLP-1 receptor agonist-associated facial volume loss. Participants will: * Schedule first dose of a prescribed GLP-1 receptor agonist drug to coincide with the baseline visit of this study * Be randomly assigned to one of two groups (Group A will receive off-label injections of hyperdiluted CaHA at Month 0. Group B will receive on-label injections of CaHA after serving as a control group through Month 6) * Have clinical photos taken at each office visit to track progress

Sponsor: Kalpna Kay Durairaj, MD, FACS

Who Can Participate

Inclusion Criteria

Adults aged 21-65 who are initiating GLP-1 therapy (semaglutide, tirzepatide, or similar) for weight loss or diabetes-related weight management with targeted weight loss of 20 pounds or more
Participants must have a body mass index (BMI) meeting indications for GLP-1 therapy and within the range of 24-32
Participants should be at the start of GLP-1 therapy (baseline visit scheduled at or within 1-2 weeks of first GLP-1 injection) so that baseline facial measurements represent their pre-weight-loss state
Participants must have noticeable facial subcutaneous fat (no pre-existing extreme lipoatrophy) and be willing to receive facial filler injections
Participants should be able to comply with all study visits and procedures up to 12 months
Participants must provide written informed consent, including consent for facial imaging

Exclusion Criteria

Participants with any prior facial cosmetic procedures that could confound results e.g. facial filler or fat transfer in the past 2 years; thread lifts or energy based device facial treatments in the last 1 year; microneedling, botulinum toxin treatment in the depressor anguli oris (DAO), or chemical peels in the last 4 months; or a history of surgical lifts and/or liposuction
Participants currently using a retinoid
Participants with active dermatologic conditions affecting the face (e.g. severe acne, psoriasis on face) or scars that would interfere with volume assessment
Participants with known allergies or hypersensitivity to CaHA or lidocaine (lidocaine allergy)
Those with a history of severe anaphylactic reactions requiring epinephrine (due to risk with injectables)
Those with uncontrolled diabetes or major comorbid conditions that would make participation unsafe (e.g. bleeding disorders that contraindicate injections, immunosuppression that raises infection risk, uncontrolled psychiatric illness such as body dysmorphic disorder)
Pregnant or breastfeeding women are excluded (GLP-1 therapies are contraindicated in pregnancy, and elective filler is avoided in pregnancy)
Women of childbearing potential must agree to use an effective contraceptive method during the study (though pregnancy during the short study window is unlikely, this is a precaution)
If a Participant becomes pregnant or initiates any new facial cosmetic treatment during the Study, they will be withdrawn
Participants planning bariatric surgery or other significant weight loss interventions (besides the GLP-1 medication) in the study period

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pasadena?

Yes, this clinical trial (NCT07419854) has an active research site in Pasadena, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Volume Loss (Soft Tissue Ptosis or Atrophy ) Treatment Options in Pasadena, CA

If you're searching for volume loss (soft tissue ptosis or atrophy ) treatment options in Pasadena, CA, this clinical trial (NCT07419854) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pasadena research site is actively enrolling participants for this clinical trial. You'll receive care from experienced volume loss (soft tissue ptosis or atrophy ) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all volume loss (soft tissue ptosis or atrophy ) clinical trials near you to find additional studies recruiting in your area.

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