Is NCT07325500 recruiting in Houston, TX?

Yes, NCT07325500 is currently recruiting participants at its Houston, TX location. This weight gain clinical trial is actively enrolling qualified participants.

How do I join the weight gain clinical trial in Houston?

To join this clinical trial in Houston, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Houston clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Weight Gain Clinical Trial in Houston, TX

About This Weight Gain Study in Houston

The objectives of this study are as follows: Primary Objective * To determine the rate of weight regain in people living with human immunodeficiency virus (HIV) (PWH) receiving semaglutide microdosing vs. no additional drug following induction therapy. Secondary Objectives * To evaluate the tolerability of semaglutide microdosing in adults with HIV. * To evaluate changes in weight, waist circumference (WC) and body mass index (BMI) over 12 weeks (W) of semaglutide weight loss induction and 48 W of semaglutide microdosing therapy.

Sponsor: The University of Texas Health Science Center, Houston

Who Can Participate

Inclusion Criteria

Confirmed human immunodeficiency virus type 1 (HIV-1)

On antiretroviral therapy (ART) for greater than or equal to 24 weeks prior to entry and no change in regimen in the 12 weeks prior to entry or planned change for the study duration

HIV-1 ribonucleic acid (RNA) \<200 copies/mL at screening

BMI greater than or equal to 30 kg/m2 or greater than or equal to 27 kg/m2 if also with greater than or equal to 1 weight-related comorbidity

If taking anti-inflammatory or blood-pressure-/lipid-/glucose-lowering medications, no change in dose for greater than or equal to 12 weeks prior to entry and no plans to dose escalate for the study duration

All participants must be willing and able to provide written informed consent and undergo all required study procedures

Exclusion Criteria

Weight greater than or equal to 400 pounds \[due to dual X-ray absorptiometry (DXA) machine limitations\] or unexplained weight change greater than or equal to 5% in the 12 weeks prior to entry

Diagnosis of or on treatment for diabetes mellitus (stable metformin dosing for pre-diabetes not excluded)

Current or planned use of medications for the treatment of obesity, or medications likely to cause significant changes in weight, during the study period

Plans to newly engage in formal, intensive physical activity or diet (such as ketogenic or very low carbohydrate) programs during the study period

Active eating disorder

Use of human growth hormone, tesamorelin or anabolic steroids \<12 weeks prior to entry, unless on a stable dose for \>24 weeks prior to entry, or plans to start any of these medications while on study

Active, severe delayed gastric emptying

Prior bariatric surgery or major gastric surgery or plans for weight reduction surgery while on study

Known retinopathy

Personal or first-degree relative history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2

Untreated, poorly controlled or previously undiagnosed thyroid disease

Chronic pancreatitis

Known allergy/sensitivity to Glucagon-Like Peptide-1 Receptor Agonist (GLP-1RA)

Poorly controlled or previously undiagnosed thyroid disease, defined as thyroid-stimulating hormone (TSH) \<0.5 or \>10 milli-international units per liter (mIU/L) at screening

Active drug or alcohol use that, in the opinion of the investigator, would interfere with adherence to study requirements

Pregnancy, nursing or plans for either during the study period

Use of planned use of any immunomodulatory therapy HIV vaccine, investigational therapy or tumor necrosis factor (TNF-α) therapy during the study period

Current serious illness requiring systemic treatment and/or hospitalization, in the opinion of site investigator

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT07325500) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Weight Gain Treatment Options in Houston, TX

If you're searching for weight gain treatment options in Houston, TX, this clinical trial (NCT07325500) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced weight gain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all weight gain clinical trials near you to find additional studies recruiting in your area.

Weight Gain Clinical Trial in Houston, TX

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