Los Angeles, CANCT06876363Now EnrollingIRB Ready

X-Linked Chronic Granulomatous Disease Clinical Trial in Los Angeles, CA

Access cutting-edge x-linked chronic granulomatous disease treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by Ensoma

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Expert Care in Los Angeles

Access x-linked chronic granulomatous disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related x-linked chronic granulomatous disease treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this x-linked chronic granulomatous disease clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This X-Linked Chronic Granulomatous Disease Study in Los Angeles

The goal of this clinical trial is to evaluate the safety and potential efficacy of the EN-374 treatment regimen and identify a dose level for further evaluation in participants with x-linked chronic granulomatous disease. The main questions it aims to answer are: * safety of the EN-374 treatment regimen * effect of the EN-374 treatment regimen on the production of functional neutrophils with NADPH oxidase activity

Sponsor: Ensoma

Who Can Participate

Inclusion Criteria

≥ 18 years of age during dose escalation, then ≥ 3 months of age during dose expansion
Diagnosis of X-CGD with DHR+ cells ≤ 5% and a pathogenic mutation in the CYBB gene
History of at least 1 severe infection requiring medical intervention or chronic inflammatory disorder
Does not have a suitable, available, and willing human leukocyte antigens (HLA)-matched (10/10) related donor
Non-sterile male participants who are or may become sexually active with female partners of childbearing potential are required to use highly effective contraception
Informed consent, with informed assent from capable participants
Adequate organ function

Exclusion Criteria

Active bacteremia or fungemia
History of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C
History or clinical evidence of any medical or social issues likely to put the participant at additional risk or to interfere with study conduct
History of HSCT or granulocyte transfusions
Known hypersensitivity to elements in the treatment regimen
Undergone investigational gene therapy
Treated with another investigational drug product within 30 days before screening
Unable to comply with the visits and requirements of the protocol as determined by the Investigator

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT06876363) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

X-Linked Chronic Granulomatous Disease Treatment Options in Los Angeles, CA

If you're searching for x-linked chronic granulomatous disease treatment options in Los Angeles, CA, this clinical trial (NCT06876363) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced x-linked chronic granulomatous disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all x-linked chronic granulomatous disease clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA