NCT06327529 · University of California, Davis
Zinc and Iron Absorption From Common Beans in Young Adult Women
What this study is about
Fifteen female study participants will be enrolled in a randomly assigned crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents.
View original scientific description
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and polyphenolic contents. Phytate, the storage form of phosphorus in plants, and polyphenols, which contribute to the varied colors of common beans, are natural components of the beans and can reduce zinc and iron bioavailability from these foods.
Interventions
OTHER
SER 118
Bean High in Phytic Acid and High in Inhibitory Polyphenols
OTHER
LMP 1001
Bean Low in Phytic Acid and High in Inhibitory Polyphenols
OTHER
LPA 586
Bean Low in Phytic Acid and Low in Inhibitory Polyphenols
OTHER
KAT B1
Bean High in Phytic Acid and Low in Inhibitory Polyphenols
Primary outcome measures
Fractional Zinc absorption
Time frame: 24 hours after first intake
amount of zinc absorbed and circulating in blood
Fractional Iron absorption
Time frame: 24 hours after first intake
amount of iron absorbed and circulating in the blood
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Healthy eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
- BMI 18.5 - 30 kg/m2
- Regular consumer of beans, i.e. ≥ 4 servings per month
- Usual iron intake estimated by Food Frequency Questionnaire to be less than the Recommended Daily Allowance (RDA) of 18 mg/d (8)
- Subject is willing and able to comply with the study protocols.
- Subject is willing to participate in all study procedures.
Exclusion criteria
- Dislike or allergy to beans
- Self-reported current or recent pregnancy (within the past 12 months)
- Self-reported recent termination of pregnancy (3 months if abortion in 1st or 2nd trimester, or 12 months if in 3rd trimester)
- Self-reported plans to become pregnant during the study period
- Self-reported cancer
- Self-reported surgery without the past 12 months
- Currently taking prescription drugs, other than for contraception, or any nutritional supplements
- Any daily iron supplementation within the past 12 months.
- Currently breastfeeding
- Any medical conditions affecting iron or zinc metabolism (such as hemochromatosis or sickle cell disease)
Where
- Davis, California
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 20, 2026 · Source of record for eligibility and locations