Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Cystic Fibrosis Clinical Trials
Cystic Fibrosis clinical trials are recruiting across 79 cities. Here are the cities with the most active studies:
Cystic Fibrosis Trial Phases
53 research organizations are sponsoring cystic fibrosis trials.
About Cystic Fibrosis
Cystic fibrosis is a genetic disorder that causes thick, sticky mucus to build up in the lungs, digestive tract, and other organs. It is caused by mutations in the CFTR gene. CFTR modulator therapies have dramatically improved outcomes, along with airway clearance techniques and nutritional support.
Clinical trials are advancing new treatments for cystic fibrosis. Currently, 74 studies are recruiting a combined 17,514 participants across the United States. Research is being conducted by 53 organizations including COPD Foundation, National Heart, Lung, and Blood Institute (NHLBI), Chris Goss and 50 others.
2026 Cystic Fibrosis Research Landscape
As of July 2026, the cystic fibrosis clinical trial landscape includes 74 actively recruiting studies across 79 cities in the United States. These studies are collectively seeking 17,514 participants, with an average enrollment target of 237 per study.
The research spans multiple phases of development: 16 studies are in NA, 14 studies are in PHASE2, 7 studies are in PHASE1, 5 studies are in PHASE4, 4 studies are in PHASE3, 3 studies are in EARLY_PHASE1. The presence of Phase 3 trials indicates that some cystic fibrosis treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 53 different organizations, including COPD Foundation, National Heart, Lung, and Blood Institute (NHLBI), Chris Goss, State University of New York at Buffalo, Children's Hospital of Philadelphia, and 48 others. The large number of sponsors reflects significant research interest and investment in cystic fibrosis treatment advancement.
Geographically, cystic fibrosis trials are most concentrated in Birmingham, Alabama (19 trials); Boston, Massachusetts (16 trials); Aurora, Colorado (12 trials); Denver, Colorado (12 trials); Kansas City, Kansas (10 trials) and 7 other cities.
Featured Cystic Fibrosis Studies
Highlighted recruiting studies for cystic fibrosis, selected by enrollment size and research scope.
Bronchiectasis and NTM Research Registry
The Bronchiectasis Research Registry is a consolidated database of non-cystic fibrosis (non-CF) Bronchiectasis and Nontuberculosis Mycobacteria (NTM) patients from multiple clinical institutions.
Role of Genetic Factors in the Development of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes directly involved in different diseases affecting the lungs of patients and healthy volu...
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
The purpose of this study is to look at pulmonary exacerbations in people with cystic fibrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms in people with CF that needs medical intervention. Both doctors and CF patients are trying to understand the best way to treat pulmo...
Frequently Asked Questions About Cystic Fibrosis Clinical Trials
Are there cystic fibrosis clinical trials near me?
Yes, there are 74 cystic fibrosis clinical trials currently recruiting across 79+ cities in the United States, including Birmingham, Alabama; Boston, Massachusetts; Aurora, Colorado. Browse the studies above to find one at a location convenient for you.
How do I join a cystic fibrosis clinical trial?
To join a cystic fibrosis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are cystic fibrosis clinical trials free?
Yes, participation in cystic fibrosis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of cystic fibrosis treatments are being studied?
Current cystic fibrosis clinical trials are testing a range of approaches across NA (16 studies), PHASE2 (14 studies), PHASE1 (7 studies), PHASE4 (5 studies), PHASE3 (4 studies), EARLY_PHASE1 (3 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 53 research organizations.
Is it safe to participate in cystic fibrosis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov