Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Moderate-to-Severe Asthma Clinical Trials
Moderate-to-Severe Asthma clinical trials are recruiting across 18 cities. Here are the cities with the most active studies:
Moderate-to-Severe Asthma Trial Phases
2 research organizations are sponsoring moderate-to-severe asthma trials.
About Moderate-to-Severe Asthma
Moderate-to-severe asthma affects patients whose symptoms are not adequately controlled with standard inhaled therapies. It accounts for 5-10% of asthma patients but drives a disproportionate share of healthcare costs. Biologic therapies targeting specific inflammatory pathways have transformed management.
Clinical trials are advancing new treatments for moderate-to-severe asthma. Currently, 2 studies are recruiting a combined 302 participants across the United States. Research is being conducted by 2 organizations including Pfizer, Enveda Therapeutics.
2026 Moderate-to-Severe Asthma Research Landscape
As of July 2026, the moderate-to-severe asthma clinical trial landscape includes 2 actively recruiting studies across 18 cities in the United States. These studies are collectively seeking 302 participants, with an average enrollment target of 151 per study.
The research spans multiple phases of development: 2 studies are in PHASE2.
Research is being led by 2 different organizations, including Pfizer, Enveda Therapeutics.
Geographically, moderate-to-severe asthma trials are most concentrated in San Jose, California (2 trials); Colorado Springs, Colorado (2 trials); Mobile, Alabama (1 trial); Chandler, Arizona (1 trial); Lancaster, California (1 trial) and 7 other cities.
Featured Moderate-to-Severe Asthma Studies
Highlighted recruiting studies for moderate-to-severe asthma, selected by enrollment size and research scope.
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected. This study is seeking participants who: * Are 18 to 70 years old * Have ...
ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
This study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and potential efficacy of ENV-294 in adults with moderate to severe asthma who are receiving background treatment with inhaled corticosteroids (ICS) and long-acting beta₂-agonists (LABA). Participants will take oral ENV-294 or placebo once daily for 12 weeks. The study includes a screening period of u...
Frequently Asked Questions About Moderate-to-Severe Asthma Clinical Trials
Are there moderate-to-severe asthma clinical trials near me?
Yes, there are 2 moderate-to-severe asthma clinical trials currently recruiting across 18+ cities in the United States, including San Jose, California; Colorado Springs, Colorado; Mobile, Alabama. Browse the studies above to find one at a location convenient for you.
How do I join a moderate-to-severe asthma clinical trial?
To join a moderate-to-severe asthma clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are moderate-to-severe asthma clinical trials free?
Yes, participation in moderate-to-severe asthma clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of moderate-to-severe asthma treatments are being studied?
Current moderate-to-severe asthma clinical trials are testing a range of approaches across PHASE2 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 2 research organizations.
Is it safe to participate in moderate-to-severe asthma clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov