Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Pemphigus Clinical Trials
Pemphigus clinical trials are recruiting across 10 cities. Here are the cities with the most active studies:
Pemphigus Trial Phases
2 research organizations are sponsoring pemphigus trials.
About Pemphigus
Pemphigus is a group of rare autoimmune blistering diseases that cause blisters on the skin and mucous membranes. Pemphigus vulgaris is the most common form. Treatment includes corticosteroids, immunosuppressants, and rituximab.
Clinical trials are advancing new treatments for pemphigus. Currently, 2 studies are recruiting a combined 190 participants across the United States. Research is being conducted by 2 organizations including University of Pennsylvania, Cabaletta Bio.
2026 Pemphigus Research Landscape
As of July 2026, the pemphigus clinical trial landscape includes 2 actively recruiting studies across 10 cities in the United States. These studies are collectively seeking 190 participants, with an average enrollment target of 95 per study.
The research spans multiple phases of development: 1 study is in PHASE1, 1 study is in PHASE2. Early-phase studies suggest new therapeutic approaches are being explored for pemphigus.
Research is being led by 2 different organizations, including University of Pennsylvania, Cabaletta Bio.
Geographically, pemphigus trials are most concentrated in Philadelphia, Pennsylvania (2 trials); Redwood City, California (1 trial); Sacramento, California (1 trial); New Haven, Connecticut (1 trial); Chicago, Illinois (1 trial) and 5 other cities.
Featured Pemphigus Studies
Highlighted recruiting studies for pemphigus, selected by enrollment size and research scope.
Autoimmune Blistering Diseases Study
Pemphigus and bullous pemphigoid (BP) are severe autoimmune blistering diseases (AIBD) that pose a critical need for new therapeutic approaches. Clinical trials in pemphigus and BP will require the availability of validated disease severity measures that can be used to define primary outcomes.
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)
A phase 1/2, open-label, safety and dosing study of autologous CART cells (desmoglein 3 chimeric autoantibody receptor T cells \[DSG3-CAART\] or CD19-specific Chimeric Antigen Receptor T cells \[CABA-201\]) in subjects with active, pemphigus vulgaris
Frequently Asked Questions About Pemphigus Clinical Trials
Are there pemphigus clinical trials near me?
Yes, there are 2 pemphigus clinical trials currently recruiting across 10+ cities in the United States, including Philadelphia, Pennsylvania; Redwood City, California; Sacramento, California. Browse the studies above to find one at a location convenient for you.
How do I join a pemphigus clinical trial?
To join a pemphigus clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are pemphigus clinical trials free?
Yes, participation in pemphigus clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of pemphigus treatments are being studied?
Current pemphigus clinical trials are testing a range of approaches across PHASE1 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 2 research organizations.
Is it safe to participate in pemphigus clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 18, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 18, 2026 · Data from ClinicalTrials.gov