Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Spina Bifida Clinical Trials
Spina Bifida clinical trials are recruiting across 18 cities. Here are the cities with the most active studies:
Spina Bifida Trial Phases
10 research organizations are sponsoring spina bifida trials.
About Spina Bifida
Spina bifida is a birth defect where the spine and spinal cord do not form properly, ranging from mild to severe forms. Myelomeningocele is the most serious type. Prevention includes folic acid supplementation before pregnancy, and treatment involves surgery, physical therapy, and ongoing management.
Clinical trials are advancing new treatments for spina bifida. Currently, 12 studies are recruiting a combined 1,362 participants across the United States. Research is being conducted by 10 organizations including David Chu, The University of Texas Health Science Center, Houston, Michael A Belfort and 7 others.
2026 Spina Bifida Research Landscape
As of July 2026, the spina bifida clinical trial landscape includes 12 actively recruiting studies across 18 cities in the United States. These studies are collectively seeking 1,362 participants, with an average enrollment target of 114 per study.
The research spans multiple phases of development: 9 studies are in NA, 1 study is in PHASE1, 1 study is in PHASE2. Early-phase studies suggest new therapeutic approaches are being explored for spina bifida.
Research is being led by 10 different organizations, including David Chu, The University of Texas Health Science Center, Houston, Michael A Belfort, University of California, Davis, Optimal Mobility, Inc, and 5 others.
Geographically, spina bifida trials are most concentrated in Houston, Texas (4 trials); Los Angeles, California (2 trials); Birmingham, Alabama (1 trial); Phoenix, Arizona (1 trial); San Francisco, California (1 trial) and 7 other cities.
Featured Spina Bifida Studies
Highlighted recruiting studies for spina bifida, selected by enrollment size and research scope.
Bowel Continence Across the Lifespan in People With Spina Bifida
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are: 1. How well do different enema programs prevent bowel accidents? 2. How do these enema programs affect independence, bow...
Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida Repair
The objective is to test the efficacy of a laparotomy-assisted fetoscopic surgical approach to cover spina bifida spinal cord developmental defects using cryopreserved human umbilical cords (NEOX Cord 1K®) as a meningeal and skin patch.
Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases
The purpose of the study is to evaluate the safety and efficacy of devices used in patients undergoing fetoscopic neural tube defect repair.
Frequently Asked Questions About Spina Bifida Clinical Trials
Are there spina bifida clinical trials near me?
Yes, there are 12 spina bifida clinical trials currently recruiting across 18+ cities in the United States, including Houston, Texas; Los Angeles, California; Birmingham, Alabama. Browse the studies above to find one at a location convenient for you.
How do I join a spina bifida clinical trial?
To join a spina bifida clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are spina bifida clinical trials free?
Yes, participation in spina bifida clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of spina bifida treatments are being studied?
Current spina bifida clinical trials are testing a range of approaches across NA (9 studies), PHASE1 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 10 research organizations.
Is it safe to participate in spina bifida clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 14, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 14, 2026 · Data from ClinicalTrials.gov