Ann Arbor, MI8 Active Studies

Advanced Solid Tumors Clinical Trials in Ann Arbor, MI

Find 8 actively recruiting advanced solid tumors clinical trials in Ann Arbor, MI. Connect with local research sites and explore new treatment options.

8
Active Trials
8
Sponsors
1,561
Enrolling

Recruiting Advanced Solid Tumors Studies in Ann Arbor

RecruitingAnn Arbor, MINCT04143711

Study of DF1001 in Patients with Advanced Solid Tumors

DF1001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase ...

378 participants
Dragonfly Therapeutics
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RecruitingAnn Arbor, MINCT05434234

A Study of YL201 in Patients With Advanced Solid Tumors

This is a phase 1, multicenter, nonrandomized, open-label, first-in-human study of YL201 conducted in China and the United States. The study will include 2 parts: a dose escalation part (Part 1) follo...

312 participants
MediLink Therapeutics (Suzhou) Co., Ltd.
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RecruitingAnn Arbor, MINCT05941507

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

This is a first-in-human, Phase 1/2 study to evaluate LCB84, a TROP2-directed antibody-drug conjugate, alone and in combination with an anti-PD-1 Ab, in dose escalation (Phase 1) followed by dose expa...

300 participants
LigaChem Biosciences, Inc.
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RecruitingAnn Arbor, MINCT06635785

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

BIPAVE-001 is a Phase 1-2 study for evaluating the safety, pharmacokinetics (PK), and efficacy of AI-081 in solid tumors....

204 participants
OncoC4, Inc.
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RecruitingAnn Arbor, MINCT05902988

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers....

120 participants
Volastra Therapeutics, Inc.
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RecruitingAnn Arbor, MINCT06399757

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-5125 for the treatment of selected locally advanced or metastatic solid tumors with particular focus o...

100 participants
Apollo Therapeutics Ltd
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RecruitingAnn Arbor, MINCT06620302

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

This phase I/II trial tests the safety, side effects and best dose of DT2216 in combination with irinotecan and how well it works in treating children, adolescents and young adults with solid tumors a...

81 participants
Children's Oncology Group
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RecruitingAnn Arbor, MINCT05988918

Multicenter Trial of ESK981 in Patients With Select Solid Tumors

This protocol will enroll patients with pancreatic adenocarcinoma and adenosquamous carcinoma (Cohort 1), gastrointestinal/pancreatic neuroendocrine neoplasms with Ki-67 \> 20% (Cohort 2) and neuroend...

66 participants
University of Michigan Rogel Cancer Center
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About Advanced Solid Tumors Clinical Trials in Ann Arbor

Advanced solid tumors refer to cancers that have grown beyond the original site or spread to distant organs. Many clinical trials enroll patients with various types of advanced solid tumors to test novel therapies. These trials often investigate immunotherapy, targeted therapy, and combination approaches.

There are currently 8 advanced solid tumors clinical trials recruiting participants in Ann Arbor, MI. These studies are seeking a combined 1,561 participants. Research is being sponsored by Dragonfly Therapeutics, MediLink Therapeutics (Suzhou) Co., Ltd., LigaChem Biosciences, Inc. and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Advanced Solid Tumors Clinical Trials in Ann Arbor — FAQ

Are there advanced solid tumors clinical trials in Ann Arbor?

Yes, there are 8 advanced solid tumors clinical trials currently recruiting in Ann Arbor, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Ann Arbor?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Ann Arbor research site will contact you about next steps.

Are clinical trials in Ann Arbor free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Ann Arbor studies also compensate for your time and travel.

What advanced solid tumors treatments are being tested?

The 8 active trials in Ann Arbor are testing new therapies including novel drugs, biologics, and treatment approaches for advanced solid tumors.

Data updated March 2, 2026 from ClinicalTrials.gov