15 Prostate Cancer Clinical Trials in Ann Arbor, MI (2026)

Q: How do I join a clinical trial in Ann Arbor?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Ann Arbor research site will contact you.

Recruiting Prostate Cancer Studies in Ann Arbor

NCT04706663Recruiting

Precision-Based Genomics in Prostate Cancer

Background: Prostate cancer is the most common cancer and the second leading cause of death in males in the United States. Researchers want to find additional gene mutations that may increase a man s...

Ann Arbor, MI2,000 participantsNational Cancer Institute (NCI)

View Study Details

NCT03784924Recruiting

EDRN Prostate MRI Biomarker Study

The commercialization of MRI fusion biopsies has resulted in a dramatic increase in the use of MRI imaging for prostate cancer. How best to use MRI in the initial prostate biopsy setting given the ava...

Ann Arbor, MI950 participantsUniversity of Michigan

View Study Details

NCT04787744Recruiting

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-...

Ann Arbor, MIPHASE2464 participantsVA Office of Research and Development

View Study Details

NCT04812366Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be...

Ann Arbor, MIPHASE2315 participantsUniversity of British Columbia

View Study Details

NCT07645391Recruiting

Targeted Early Detection Program in Men at High Genetic Risk for Prostate Cancer

This study evaluates urinary biomarkers and PSA to help determine the best approach to early detection of prostate cancer in patients with an elevated familial risk....

Ann Arbor, MI200 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

NCT04986423Recruiting

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

This is an open-label, randomized, Phase 2b study of ZEN003694 in combination with enzalutamide vs. enzalutamide monotherapy in patients with mCRPC who have progressed on prior abiraterone by PCWG3 cr...

Ann Arbor, MIPHASE2200 participantsZenith Epigenetics

View Study Details

NCT07181161Recruiting

Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

The main purpose of this study is to assess the safety and tolerability of AZD0516 as monotherapy and/or in combination with other anti-cancer agents for treatment of metastatic prostate cancer....

Ann Arbor, MIPHASE1177 participantsAstraZeneca

View Study Details

NCT05038332Recruiting

Post-prostatectomy Radiation Therapy--Moderate Versus Ultra-hypofractionated (Also Known as Stereotactic Body Radiation Therapy [SBRT])

The primary purpose of this study is to compare the quality of life (QOL) reported by prostate cancer patients 2 years after treatment with ultra-hypofractionated post-prostatectomy radiation therapy ...

Ann Arbor, MIPHASE2136 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

NCT04038502Recruiting

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

This is an unblinded, randomized clinical study comparing the efficacy of DNA damaging chemotherapy using carboplatin, to standard of care therapy for patients who have metastatic castrate resistant p...

Ann Arbor, MIPHASE2100 participantsVA Office of Research and Development

View Study Details

NCT07096999Recruiting

SPECT/CT Imaging for Dosimetry in 177Lu-PSMA-617 (Pluvicto) Therapy

This study is being performed to establish the association between absorbed dose to tumor and response and absorbed dose to normal organs and toxicity following Lu177-PSMA radioligand therapy...

Ann Arbor, MI60 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

NCT06084338Recruiting

Randomized Phase II Trial of Targeted Radiation With no Castration for Mcrpc

This trial tests if the combination of comprehensive metastasis directed therapy delivered by a precision form of external beam radiotherapy (stereotactic ablative radiotherapy), combined with PSMA ta...

Ann Arbor, MIPHASE260 participantsVA Office of Research and Development

View Study Details

NCT06228053Recruiting

Study of SX-682 Plus Enzalutamide in Men With Abiraterone-Resistant Metastatic Castration Resistant Prostate Cancer

The goal of this clinical trial is to study the combination of SX-682 plus enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC) who have failed abiraterone....

Ann Arbor, MIPHASE253 participantsSyntrix Biosystems, Inc.

View Study Details

NCT05965180Recruiting

Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe

In this project, we will integrate the Photoacoustic (PA) technology into a prostate biopsy procedure through a fine needle probe. The needle probe will be in the shape of a biopsy needle and compatib...

Ann Arbor, MI50 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

NCT07050433Recruiting

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

This study is a companion to the SYNERGY-201 clinical trial (NCT06228053), which investigates SX-682 and enzalutamide in individuals with prostate cancer. Individuals must be participating in SYNERGY-...

Ann Arbor, MI48 participantsDuke University

View Study Details

NCT06616155Recruiting

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

This phase I/II tests the safety, side effects and best dose of ruxolitinib in combination with enzalutamide and how well it works in treating patients with prostate cancer that remains despite blocki...

Ann Arbor, MIPHASE120 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

About Prostate Cancer Clinical Trials in Ann Arbor

Prostate cancer develops in the prostate gland and is one of the most common cancers in men. Many prostate cancers grow slowly, but some can be aggressive. Treatment options range from active surveillance to surgery, radiation, and hormone therapy.

There are currently 15 prostate cancer clinical trials recruiting participants in Ann Arbor, MI. These studies are seeking a combined 4,833 participants. Research is being sponsored by National Cancer Institute (NCI), University of Michigan, VA Office of Research and Development and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Prostate Cancer Clinical Trials in Ann Arbor — FAQ

Are there prostate cancer clinical trials in Ann Arbor?

Yes, there are 15 prostate cancer clinical trials currently recruiting in Ann Arbor, MI. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Ann Arbor?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Ann Arbor research site will contact you about next steps.

Are clinical trials in Ann Arbor free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Ann Arbor studies also compensate for your time and travel.

What prostate cancer treatments are being tested?

The 15 active trials in Ann Arbor are testing new therapies including novel drugs, biologics, and treatment approaches for prostate cancer.

Data updated July 17, 2026 from ClinicalTrials.gov