Aurora, CO8 Active Studies

Brain Cancer Clinical Trials in Aurora, CO

Find 8 actively recruiting brain cancer clinical trials in Aurora, CO. Connect with local research sites and explore new treatment options.

8
Active Trials
6
Sponsors
2,793
Enrolling

Recruiting Brain Cancer Studies in Aurora

RecruitingAurora, CONCT03970447

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple...

1,280 participants
Global Coalition for Adaptive Research
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RecruitingAurora, CONCT05902169

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier prope...

560 participants
CarThera
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RecruitingAurora, CONCT05566795

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in ...

400 participants
Day One Biopharmaceuticals, Inc.
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RecruitingAurora, CONCT04804644

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the...

200 participants
NRG Oncology
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RecruitingAurora, CONCT05096481

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

This study will address the question of whether targeting CMV antigens with PEP-CMV can serve as a novel immunotherapeutic approach in pediatric patients with newly-diagnosed high-grade glioma (HGG) o...

120 participants
Nationwide Children's Hospital
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RecruitingAurora, CONCT05843253

Study of Ribociclib and Everolimus in HGG and DIPG

The goal of this study is to determine the efficacy of the study drugs ribociclib and everolimus to treat pediatric and young adult patients newly diagnosed with a high-grade glioma (HGG), including D...

108 participants
Nationwide Children's Hospital
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RecruitingAurora, CONCT05278208

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

This study will evaluate the safety and efficacy of Lutathera (177Lu-DOTATATE) in patients with progressive or recurrent High-Grade Central Nervous System (CNS) tumors and meningiomas that demonstrate...

65 participants
Nationwide Children's Hospital
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RecruitingAurora, CONCT06161974

Study of Olutasidenib and Temozolomide in HGG

The goal of this study is to determine the efficacy of the study drug olutasidenib to treat newly diagnosed pediatric and young adult patients with a high-grade glioma (HGG) harboring an IDH1 mutation...

60 participants
Rigel Pharmaceuticals
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About Brain Cancer Clinical Trials in Aurora

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 8 brain cancer clinical trials recruiting participants in Aurora, CO. These studies are seeking a combined 2,793 participants. Research is being sponsored by Global Coalition for Adaptive Research, CarThera, Day One Biopharmaceuticals, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in Aurora — FAQ

Are there brain cancer clinical trials in Aurora?

Yes, there are 8 brain cancer clinical trials currently recruiting in Aurora, CO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Aurora?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Aurora research site will contact you about next steps.

Are clinical trials in Aurora free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Aurora studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 8 active trials in Aurora are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated March 2, 2026 from ClinicalTrials.gov