Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Brain Cancer Clinical Trials
Brain Cancer clinical trials are recruiting across 120 cities. Here are the cities with the most active studies:
Brain Cancer Trial Phases
62 research organizations are sponsoring brain cancer trials.
About Brain Cancer
Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.
Clinical trials are advancing new treatments for brain cancer. Currently, 100 studies are recruiting a combined 52,616 participants across the United States. Research is being conducted by 62 organizations including M.D. Anderson Cancer Center, Adela, Inc, University of Florida and 59 others.
2026 Brain Cancer Research Landscape
As of July 2026, the brain cancer clinical trial landscape includes 100 actively recruiting studies across 120 cities in the United States. These studies are collectively seeking 52,616 participants, with an average enrollment target of 526 per study.
The research spans multiple phases of development: 35 studies are in PHASE2, 21 studies are in NA, 15 studies are in PHASE1, 13 studies are in PHASE3, 1 study is in PHASE4. The presence of Phase 3 trials indicates that some brain cancer treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 62 different organizations, including M.D. Anderson Cancer Center, Adela, Inc, University of Florida, CureScience, Global Coalition for Adaptive Research, and 57 others. The large number of sponsors reflects significant research interest and investment in brain cancer treatment advancement.
Geographically, brain cancer trials are most concentrated in Boston, Massachusetts (23 trials); San Francisco, California (20 trials); Los Angeles, California (16 trials); Houston, Texas (13 trials); Rochester, Minnesota (12 trials) and 7 other cities.
Featured Brain Cancer Studies
Highlighted recruiting studies for brain cancer, selected by enrollment size and research scope.
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
This study performs standardized testing of tumor tissue samples to learn which genes are mutated (have changed) in order to provide personalized cancer therapy options to cancer patients at MD Anderson. This may help doctors use testing information on tumors to identify clinical trials that may be most relevant to patients. Researchers may also use the information learned from this study to devel...
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gastric, head and neck, hepatobiliary, leukemia, lung, lymphoma, multiple myeloma, ovarian, pancreatic, p...
Florida Center for Brain Tumor Research
The purpose of this research study is to collect and store brain tumor tissue samples for future research. The samples will become part of the University of Florida Brain Tumor Tissue Bank/Florida Center for Brain Tumor Research. The goal is to find improved treatments and cures for brain tumors.
Frequently Asked Questions About Brain Cancer Clinical Trials
Are there brain cancer clinical trials near me?
Yes, there are 100 brain cancer clinical trials currently recruiting across 120+ cities in the United States, including Boston, Massachusetts; San Francisco, California; Los Angeles, California. Browse the studies above to find one at a location convenient for you.
How do I join a brain cancer clinical trial?
To join a brain cancer clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are brain cancer clinical trials free?
Yes, participation in brain cancer clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of brain cancer treatments are being studied?
Current brain cancer clinical trials are testing a range of approaches across PHASE2 (35 studies), NA (21 studies), PHASE1 (15 studies), PHASE3 (13 studies), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 62 research organizations.
Is it safe to participate in brain cancer clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov