Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Melanoma Clinical Trials
Melanoma clinical trials are recruiting across 124 cities. Here are the cities with the most active studies:
Melanoma Trial Phases
64 research organizations are sponsoring melanoma trials.
About Melanoma
Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.
Clinical trials are advancing new treatments for melanoma. Currently, 100 studies are recruiting a combined 38,646 participants across the United States. Research is being conducted by 64 organizations including M.D. Anderson Cancer Center, Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI) and 61 others.
2026 Melanoma Research Landscape
As of July 2026, the melanoma clinical trial landscape includes 100 actively recruiting studies across 124 cities in the United States. These studies are collectively seeking 38,646 participants, with an average enrollment target of 386 per study.
The research spans multiple phases of development: 40 studies are in PHASE2, 23 studies are in PHASE1, 17 studies are in NA, 15 studies are in PHASE3, 2 studies are in PHASE4, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some melanoma treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 64 different organizations, including M.D. Anderson Cancer Center, Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI), Melanoma and Skin Cancer Trials Limited, H. Lee Moffitt Cancer Center and Research Institute, and 59 others. The large number of sponsors reflects significant research interest and investment in melanoma treatment advancement.
Geographically, melanoma trials are most concentrated in Los Angeles, California (21 trials); Houston, Texas (12 trials); New York, New York (11 trials); Aurora, Colorado (11 trials); Tampa, Florida (10 trials) and 7 other cities.
Featured Melanoma Studies
Highlighted recruiting studies for melanoma, selected by enrollment size and research scope.
Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma
This study investigates the extent to which lifestyle factors including mental health, social support, diet, and exercise are associated with quality of life and melanoma patient outcomes. Knowledge gained from this study may be used to guide the design of prospective clinical trials of lifestyle interventions to improve the outcomes of melanoma patients and assist doctors in counseling their pati...
Storage and Research Use of Human Bio-specimens From Melanoma Patients and Clinical Testing for Assignment of Treatment
The purpose of this research is to identify biological characteristics occurring in the initiation and progression of melanoma.
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
This study will investigate how genetic and environmental factors contribute to the development of melanoma, a type of skin cancer, and related conditions. Individuals \>=4 weeks with a personal or family history of melanoma or atypical spitzoid/Spitz tumor may be eligible for this study. Participants will: * Fill out one or two questionnaires about their personal and family medical history. * P...
Frequently Asked Questions About Melanoma Clinical Trials
Are there melanoma clinical trials near me?
Yes, there are 100 melanoma clinical trials currently recruiting across 124+ cities in the United States, including Los Angeles, California; Houston, Texas; New York, New York. Browse the studies above to find one at a location convenient for you.
How do I join a melanoma clinical trial?
To join a melanoma clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are melanoma clinical trials free?
Yes, participation in melanoma clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of melanoma treatments are being studied?
Current melanoma clinical trials are testing a range of approaches across PHASE2 (40 studies), PHASE1 (23 studies), NA (17 studies), PHASE3 (15 studies), PHASE4 (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 64 research organizations.
Is it safe to participate in melanoma clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 17, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov