Tampa, FLORIDA7 Active Studies

Melanoma Clinical Trials in Tampa, FLORIDA

Find 7 actively recruiting melanoma clinical trials in Tampa, FLORIDA. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,216
Enrolling

Recruiting Melanoma Studies in Tampa

RecruitingTampa, FLORIDANCT05987332

IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive eit...

420 participants
IDEAYA Biosciences
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RecruitingTampa, FLORIDANCT06743126

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

This clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and tolerability of treatment wit...

360 participants
Immatics US, Inc.
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RecruitingTampa, FLORIDANCT03567889

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients

The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of...

186 participants
Philogen S.p.A.
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RecruitingTampa, FLORIDANCT06007690

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

The primary objective is to determine the safety and efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indeterminate lesions (IL) or small choroidal melano...

100 participants
Aura Biosciences
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RecruitingTampa, FLORIDANCT04349436

A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies

This Phase 1B/2 study is a multicenter, open-label, study of RP1 to investigate the (a) objective response rate, in addition to (b) safety and tolerability of RP1 for the treatment of advanced cutaneo...

65 participants
Replimune Inc.
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RecruitingTampa, FLORIDANCT05361174

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung cancer (NSCLC)....

53 participants
Iovance Biotherapeutics, Inc.
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RecruitingTampa, FLORIDANCT06121180

Study of Cemiplimab Plus Ziv-Aflibercept for Subjects With Metastatic Uveal Melanoma

The goal of this clinical research study is to find out if Cemiplimab plus Ziv-Aflibercept is safe and effective in treating your condition of metastatic (spread to other parts of your body) uveal mel...

32 participants
H. Lee Moffitt Cancer Center and Research Institute
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About Melanoma Clinical Trials in Tampa

Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.

There are currently 7 melanoma clinical trials recruiting participants in Tampa, FLORIDA. These studies are seeking a combined 1,216 participants. Research is being sponsored by IDEAYA Biosciences, Immatics US, Inc., Philogen S.p.A. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Melanoma Clinical Trials in Tampa — FAQ

Are there melanoma clinical trials in Tampa?

Yes, there are 7 melanoma clinical trials currently recruiting in Tampa, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Tampa?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Tampa research site will contact you about next steps.

Are clinical trials in Tampa free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Tampa studies also compensate for your time and travel.

What melanoma treatments are being tested?

The 7 active trials in Tampa are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.

Data updated March 2, 2026 from ClinicalTrials.gov