Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma

OTHER

Medical Chart Review

Medical charts are reviewed

OTHER

Questionnaire Administration

Complete questionnaires

Change in depression/distress

Time frame: Up to 10 years

Will be assessed using the Centers for Epidemiologic Studies - Depression. Lifetime history of Major Depressive Disorder (MDD) will be measured using the two cardinal items from the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV Disorder. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

Change in anxiety

Time frame: Up to 10 years

Will be assessed using the Speilberger State/Trait Anxiety Inventory. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

Change in cancer-related symptoms

Time frame: Up to 10 years

Will be assessed using the MD Anderson Symptom Inventory. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

Change in social support

Time frame: Up to 10 years

Will be assessed using the 24-item Social Provisions Scale. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

Change in general eating habits

Time frame: Up to 10 years

Will be assessed using the National Cancer Institute National Health and Nutrition Examination Survey Dietary Screener Questionnaire, and optionally, the National Institutes of Health Automated Self-Administered 24-hour.

Change in physical activity

Time frame: Up to 10 years

Will be assessed using the Godin Leisure -Time Exercise Questionnaire. Multivariate methods, including repeated measures analyses, will be employed to further explore the potential changes in the measures over time.

Associations between mental health, social support, diet and exercise behaviors, and quality of life and demographic variables

Time frame: Up to 10 years

Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

Effect of diet, physical activity, depressive symptoms, distress, lifetime MDD, and social support on progression free survival

Time frame: Up to 10 years

Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

Effect of diet, physical activity, depressive symptoms, distress, lifetime MDD, and social support on cancer mortality

Time frame: Up to 10 years

Will be evaluated using Pearson's product moment correlation coefficients together with scatterplots where appropriate.

Response to treatment

Time frame: Up to 10 years

Logistic regression models will be used to measure the association of diet, physical activity, diet, depressive symptoms, distress, lifetime MDD, and social support and response to treatment at each time point.

What is a clinical trial?

A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.

Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.

Will I be compensated?

Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.

Will I receive a placebo instead of treatment?

When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.

Can I leave a trial if I change my mind?

Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.

How long does a clinical trial last?

Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.