74 Active Studies

Kidney Cancer Clinical Trials Near You

Also searched as: renal cancer, RCC, renal cell carcinoma, kidney tumor clinical trials

Find 74 actively recruiting kidney cancer research studies near you. Connect with study sites, check eligibility, and explore new treatment options.

74Active Trials
108+Locations
28,180Participants Needed

Recruiting Studies

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Data: ClinicalTrials.gov · Source of record for eligibility and locations

Top Cities for Kidney Cancer Clinical Trials

Kidney Cancer clinical trials are recruiting across 108 cities. Here are the cities with the most active studies:

Kidney Cancer Trial Phases

PHASE2(36 studies)
PHASE1(23 studies)
PHASE3(8 studies)
NA(6 studies)
EARLY_PHASE1(2 studies)

49 research organizations are sponsoring kidney cancer trials.

About Kidney Cancer

Kidney cancer, most commonly renal cell carcinoma, develops in the lining of the kidney tubules. It accounts for about 3-5% of all adult cancers. Treatment includes surgery, targeted therapy, immunotherapy, and radiation.

Clinical trials are advancing new treatments for kidney cancer. Currently, 74 studies are recruiting a combined 28,180 participants across the United States. Research is being conducted by 49 organizations including Azienda Ospedaliero-Universitaria Careggi, National Cancer Institute (NCI), Exelixis and 46 others.

2026 Kidney Cancer Research Landscape

As of July 2026, the kidney cancer clinical trial landscape includes 74 actively recruiting studies across 108 cities in the United States. These studies are collectively seeking 28,180 participants, with an average enrollment target of 381 per study.

The research spans multiple phases of development: 36 studies are in PHASE2, 23 studies are in PHASE1, 8 studies are in PHASE3, 6 studies are in NA, 2 studies are in EARLY_PHASE1. The presence of Phase 3 trials indicates that some kidney cancer treatments are in late-stage testing and may be approaching regulatory review.

Research is being led by 49 different organizations, including Azienda Ospedaliero-Universitaria Careggi, National Cancer Institute (NCI), Exelixis, Alliance for Clinical Trials in Oncology, Merck Sharp & Dohme LLC, and 44 others. The large number of sponsors reflects significant research interest and investment in kidney cancer treatment advancement.

Geographically, kidney cancer trials are most concentrated in New York, New York (14 trials); Dallas, Texas (10 trials); Duarte, California (9 trials); Boston, Massachusetts (9 trials); Houston, Texas (9 trials) and 7 other cities.

Featured Kidney Cancer Studies

Highlighted recruiting studies for kidney cancer, selected by enrollment size and research scope.

RecruitingNCT05363657

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors

Partial nephrectomy (PN) is the standard treatment for localized renal masses and should be preferred in clinical T1 (\<7 cm tumor diameter) renal tumors over radical nephrectomy (RN) whenever technically feasible. Nonetheless, indications, approaches, techniques for PN, and correct reporting of outcomes, are still a matter of great debate within the urology community. Concurrently, case-report se...

Sponsor: Azienda Ospedaliero-Universitaria Careggi· 10,000 participants· 7 locations (Los Angeles, San Diego, Stanford, Chicago)
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RecruitingNCT00001238

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled. Affected individuals or individuals suspected of having a germline urologic malignant disorder will undergo periodic clinical assessment and genetic analyses for the purpose of: 1) definiti...

Sponsor: National Cancer Institute (NCI)· 5,000 participants· 1 location (Bethesda)
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RecruitingNCT05176483 · PHASE1

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect of biomarkers of zanzalintinib administered alone, and in combination with nivolumab (doublet), nivolumab + ipilimumab (triplet) and nivolumab + relatlimab (triplet) in participants with advanced solid tumors....

Sponsor: Exelixis· 1,314 participants· 10 locations (Phoenix, Tucson, Palo Alto, Santa Barbara)
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Frequently Asked Questions About Kidney Cancer Clinical Trials

Are there kidney cancer clinical trials near me?

Yes, there are 74 kidney cancer clinical trials currently recruiting across 108+ cities in the United States, including New York, New York; Dallas, Texas; Duarte, California. Browse the studies above to find one at a location convenient for you.

How do I join a kidney cancer clinical trial?

To join a kidney cancer clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.

Are kidney cancer clinical trials free?

Yes, participation in kidney cancer clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.

What types of kidney cancer treatments are being studied?

Current kidney cancer clinical trials are testing a range of approaches across PHASE2 (36 studies), PHASE1 (23 studies), PHASE3 (8 studies), NA (6 studies), EARLY_PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 49 research organizations.

Is it safe to participate in kidney cancer clinical trials?

Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.

Data updated July 17, 2026 from ClinicalTrials.gov

About This Data

Data: ClinicalTrials.gov · Source of record for eligibility and locations

Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.

Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.

Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov