Jacksonville, FLORIDA6 Active Studies

Brain Cancer Clinical Trials in Jacksonville, FLORIDA

Find 6 actively recruiting brain cancer clinical trials in Jacksonville, FLORIDA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
2,924
Enrolling

Recruiting Brain Cancer Studies in Jacksonville

RecruitingJacksonville, FLORIDANCT03970447

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/III response adaptive randomization platform trial designed to evaluate multiple...

1,280 participants
Global Coalition for Adaptive Research
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RecruitingJacksonville, FLORIDANCT06556563

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

This is a multicenter, two-arm, randomized, double-blind, placebo-controlled study of Optune® (Tumor Treating Fields at 200 kHz) together with maintenance Temozolomide (TMZ) chemotherapy agent and pem...

741 participants
NovoCure GmbH
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RecruitingJacksonville, FLORIDANCT05902169

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

The brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls. Because of these barrier prope...

560 participants
CarThera
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RecruitingJacksonville, FLORIDANCT03750227

Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

This phase III trial studies the side effects and how well stereotactic radiosurgery (SRS) works before or after surgery in patients with tumors that has spread to the brain or that can be removed by ...

140 participants
Mayo Clinic
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RecruitingJacksonville, FLORIDANCT06160206

Retifanlimab with Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma

This phase II trial tests how well retifanlimab with bevacizumab and hypofractionated radiotherapy, compared to bevacizumab and hypofractionated radiotherapy alone, works in treating patients with gli...

134 participants
Academic and Community Cancer Research United
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RecruitingJacksonville, FLORIDANCT05222620

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

This phase II trial compares the effect of single fraction stereotactic radiosurgery to fractionated stereotactic radiosurgery for the treatment of patients with cancer that has spread to the brain (m...

69 participants
Mayo Clinic
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About Brain Cancer Clinical Trials in Jacksonville

Brain cancer includes tumors that originate in the brain (primary) or spread from other areas (metastatic). Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Treatment typically combines surgery, radiation, and chemotherapy, with immunotherapy trials underway.

There are currently 6 brain cancer clinical trials recruiting participants in Jacksonville, FLORIDA. These studies are seeking a combined 2,924 participants. Research is being sponsored by Global Coalition for Adaptive Research, NovoCure GmbH, CarThera and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Brain Cancer Clinical Trials in Jacksonville — FAQ

Are there brain cancer clinical trials in Jacksonville?

Yes, there are 6 brain cancer clinical trials currently recruiting in Jacksonville, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What brain cancer treatments are being tested?

The 6 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for brain cancer.

Data updated March 2, 2026 from ClinicalTrials.gov