Jacksonville, FLORIDA5 Active Studies

Colorectal Cancer Clinical Trials in Jacksonville, FLORIDA

Find 5 actively recruiting colorectal cancer clinical trials in Jacksonville, FLORIDA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
2,237
Enrolling

Recruiting Colorectal Cancer Studies in Jacksonville

RecruitingJacksonville, FLORIDANCT06445062

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors combined with Standard(s) of Care (SOC...

1,130 participants
Revolution Medicines, Inc.
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RecruitingJacksonville, FLORIDANCT06252649

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

The aim of this study is to compare progression free survival (PFS) in treatment-naïve participants with KRAS p.G12C mutated metastatic colorectal cancer (mCRC) receiving sotorasib, panitumumab and FO...

450 participants
Amgen
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RecruitingJacksonville, FLORIDANCT04486378

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected ...

327 participants
BioNTech SE
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RecruitingJacksonville, FLORIDANCT06107413

Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events and change in disease activity when ABBV-400 is gi...

280 participants
AbbVie
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RecruitingJacksonville, FLORIDANCT05961709

The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer

To learn if cemiplimab can help to control dMMR colon cancer....

50 participants
M.D. Anderson Cancer Center
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About Colorectal Cancer Clinical Trials in Jacksonville

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 5 colorectal cancer clinical trials recruiting participants in Jacksonville, FLORIDA. These studies are seeking a combined 2,237 participants. Research is being sponsored by Revolution Medicines, Inc., Amgen, BioNTech SE and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Jacksonville — FAQ

Are there colorectal cancer clinical trials in Jacksonville?

Yes, there are 5 colorectal cancer clinical trials currently recruiting in Jacksonville, FLORIDA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 5 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated March 2, 2026 from ClinicalTrials.gov