11 Colorectal Cancer Clinical Trials in Aurora, IL (2026)

Q: How do I join a clinical trial in Aurora?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Aurora research site will contact you.

Recruiting Colorectal Cancer Studies in Aurora

NCT06682650Recruiting

Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)

Although implementation intentions (I2)-based tools enhance colorectal cancer (CRC) screening uptake, prior studies have not tested their implementation into routine primary care delivery. In this stu...

Aurora, IL2,200 participantsUniversity of Kansas Medical Center

View Study Details

NCT06445062Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors combined with Standard(s) of Care (SOC...

Aurora, IL1,130 participantsRevolution Medicines, Inc.

View Study Details

NCT05410977Recruiting

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening technique for the detection of colorectal cance...

Aurora, IL950 participantsMayo Clinic

View Study Details

NCT06073431Recruiting

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

This study evaluates cancer-related weight and muscle mass loss, symptoms, and physical function (cachexia) in patients undergoing treatment for colorectal, lung, or pancreatic cancer that cannot be r...

Aurora, IL800 participantsUniversity of Rochester

View Study Details

NCT07284849Recruiting

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

The purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of metastatic microsatellite sta...

Aurora, IL700 participantsIncyte Corporation

View Study Details

NCT04929223Recruiting

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combinations, in participants with metastatic colorectal c...

Aurora, IL542 participantsHoffmann-La Roche

View Study Details

NCT05863195Recruiting

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemotherapy alone in treating patients with colo...

Aurora, IL408 participantsECOG-ACRIN Cancer Research Group

View Study Details

NCT04184973Recruiting

Efficacy and Safety of the CG-100 Intraluminal Bypass Device

A randomized trial to assess the safety and efficacy of CG-100 for reducing stoma creation rate in subjects undergoing mesorectal excision....

Aurora, IL250 participantsColospan Ltd.

View Study Details

NCT05319314Recruiting

LYL273 for Patients With Relapsed or Refractory mCRC

This is a Phase 1/2 open-label, multicenter study evaluating the safety and efficacy of LYL273 in participants with relapsed or refractory metastatic colorectal cancer....

Aurora, IL155 participantsLyell Immunopharma, Inc.

View Study Details

NCT07235293Recruiting

A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.

This clinical study is testing whether a new combination of medicines (DSP107 and atezolizumab) is more effective and safer than an existing treatment (fruquintinib) for people with advanced colorecta...

Aurora, IL90 participantsKahr Bio Australia Pty Ltd

View Study Details

NCT05840263Recruiting

Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer

The overall objective of this study is to develop a novel couple-based mindfulness intervention aimed at reducing distress in patients with metastatic colorectal cancer (mCRC) and their partners....

Aurora, IL48 participantsUniversity of Colorado, Denver

View Study Details

About Colorectal Cancer Clinical Trials in Aurora

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 11 colorectal cancer clinical trials recruiting participants in Aurora, IL. These studies are seeking a combined 7,273 participants. Research is being sponsored by University of Kansas Medical Center, Revolution Medicines, Inc., Mayo Clinic and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Aurora — FAQ

Are there colorectal cancer clinical trials in Aurora?

Yes, there are 11 colorectal cancer clinical trials currently recruiting in Aurora, IL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Aurora?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Aurora research site will contact you about next steps.

Are clinical trials in Aurora free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Aurora studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 11 active trials in Aurora are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated July 13, 2026 from ClinicalTrials.gov