Aurora, IL21 Active Studies

Type 1 Diabetes Clinical Trials in Aurora, IL

Find 21 actively recruiting type 1 diabetes clinical trials in Aurora, IL. Connect with local research sites and explore new treatment options.

21
Active Trials
14
Sponsors
9,267
Enrolling

Recruiting Type 1 Diabetes Studies in Aurora

NCT06141434Recruiting

PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life

This research study is called 'PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life: The PROMISE Study'. The purpose of this study is to find out more about how exposures d...

Aurora, IL6,000 participantsUniversity of Colorado, Denver
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NCT07088068Recruiting

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

This is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase 3, 2-arm study for treatment. The purpose of this study is to measure change in glycemic control and prandial insul...

Aurora, IL723 participantsSanofi
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NCT07228117Recruiting

GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes

The purpose of this study is to check that a new insulin pump, called NMX8, is safe when used with a continuous glucose monitoring sensor called Disposable Sensor 5/Simplera Sync in people with diabet...

Aurora, IL400 participantsMedtronic MiniMed, Inc.
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NCT07011147Recruiting

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

The goal of this randomized controlled trial is to compare the efficacy and safety of the iLet Bionic Pancreas (BP) System in adults with insulin-treated diabetes (type 1 diabetes or type 2 diabetes) ...

Aurora, IL240 participantsUniversity of Colorado, Denver
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NCT06618027Recruiting

Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes

Type 1 diabetes (T1D) is a common chronic illness among children requiring a high degree of self-management for good glycemic control. Adolescents are at risk for poor disease management and health ou...

Aurora, IL200 participantsChildren's National Research Institute
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NCT06481904Recruiting

Registry for Stage 2 Type 1 Diabetes

Stage 2 Type 1 Diabates (T1D) is an early stage of T1D characterized by dysglycemia but not yet leading to clinical symptoms. Progression of the disease to Stage 3 (clinical T1D), leads to overt hyper...

Aurora, IL200 participantsSanofi
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NCT05762107Recruiting

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

The goal of this clinical trial is to learn about the effect of the study drug (ZT-01) on low blood sugar (hypoglycemia) in adults with type 1 diabetes (T1D) who have been having low blood sugars ("hy...

Aurora, IL186 participantsZucara Therapeutics Inc.
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NCT07187531Recruiting

SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes

This is a Phase 2b, investigator- and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Typ...

Aurora, IL159 participantsSAb Biotherapeutics, Inc.
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NCT06297980Recruiting

Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes

The objectives of this study are to examine how sex hormones (use of hormonal birth control, menstrual cycle phase) impact glycemic control among women with type 1 diabetes (T1D), and to test adjustme...

Aurora, IL150 participantsUniversity of Colorado, Denver
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NCT06217302Recruiting

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Wheth...

Aurora, IL150 participantsAlessandro Doria
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NCT06575842Recruiting

Accuracy of Continuous Glucose Monitors During the Perioperative Period in Youth With Type 1 Diabetes

This study is assessing the accuracy of continuous glucose monitors during surgical procedures requiring anesthesia....

Aurora, IL120 participantsUniversity of Colorado, Denver
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NCT07061574Recruiting

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from randomization in person...

Aurora, IL120 participantsCity of Hope Medical Center
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NCT02734277Recruiting

Type 1 Diabetes Extension Study

This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodula...

Aurora, IL111 participantsNational Institute of Allergy and Infectious Diseases (NIAID)
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NCT07224321Recruiting

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to \<18 year...

Aurora, IL100 participantsMannkind Corporation
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NCT06783309Recruiting

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103. The approximately 208-da...

Aurora, IL72 participantsCOUR Pharmaceutical Development Company, Inc.
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NCT07142252Recruiting

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

This Phase 2 study is a 2-arm, multi-center, double-masked (masking of the participant, care provider and investigator), placebo-controlled, 2:1 randomized trial design in new onset T1D participants (...

Aurora, IL66 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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NCT06455319Recruiting

Precision Administration of Anti-thymocyte Globulin With or Without Verapamil

T cell directed therapy, anti-thymocyte globulin (ATG), in low doses, has been shown to lower HbA1c and preserve endogenous insulin production (measured by C-peptide) in individuals with recently diag...

Aurora, IL60 participantsUniversity of Florida
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NCT05065372Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

Diabetic kidney disease and cardiovascular disease remain the leading causes of morbidity and mortality in people with type 1 diabetes and are exacerbated with longer duration of diabetes and time out...

Aurora, IL60 participantsKalie Tommerdahl
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NCT05819138Recruiting

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes

This trial plans to learn more about the effects of a medication, semaglutide, on cardiovascular function, kidney function, and insulin sensitivity in adults with type 1 diabetes. This medication has ...

Aurora, IL60 participantsUniversity of Colorado, Denver
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NCT06627504Recruiting

Type 1 Diabetes REst for Metabolic Health

Research has shown a link between poor sleep health and late circadian timing with cardiometabolic health in adolescents with type 1 diabetes (T1D). Cardiovascular disease (CVD) is the leading cause o...

Aurora, IL50 participantsUniversity of Colorado, Denver
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NCT06575790Recruiting

Using Simplified Meal Boluses Versus Carbohydrate Counting in Adolescents With Hybrid Closed Loop Systems

The goal of this trial is to evaluate blood sugar control in patients with type 1 diabetes when using a simple meal bolus strategy (small, medium, large meals) compared to carbohydrate counting when o...

Aurora, IL40 participantsUniversity of Colorado, Denver
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About Type 1 Diabetes Clinical Trials in Aurora

Type 1 diabetes is an autoimmune condition where the immune system destroys insulin-producing beta cells in the pancreas. It typically develops in childhood or young adulthood and requires lifelong insulin therapy. Research is exploring artificial pancreas systems, immunotherapy, and beta cell replacement.

There are currently 21 type 1 diabetes clinical trials recruiting participants in Aurora, IL. These studies are seeking a combined 9,267 participants. Research is being sponsored by University of Colorado, Denver, Sanofi, Medtronic MiniMed, Inc. and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Type 1 Diabetes Clinical Trials in Aurora — FAQ

Are there type 1 diabetes clinical trials in Aurora?

Yes, there are 21 type 1 diabetes clinical trials currently recruiting in Aurora, IL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Aurora?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Aurora research site will contact you about next steps.

Are clinical trials in Aurora free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Aurora studies also compensate for your time and travel.

What type 1 diabetes treatments are being tested?

The 21 active trials in Aurora are testing new therapies including novel drugs, biologics, and treatment approaches for type 1 diabetes.

Data updated July 13, 2026 from ClinicalTrials.gov