Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Type 1 Diabetes Clinical Trials
Type 1 Diabetes clinical trials are recruiting across 103 cities. Here are the cities with the most active studies:
Type 1 Diabetes Trial Phases
70 research organizations are sponsoring type 1 diabetes trials.
About Type 1 Diabetes
Type 1 diabetes is an autoimmune condition where the immune system destroys insulin-producing beta cells in the pancreas. It typically develops in childhood or young adulthood and requires lifelong insulin therapy. Research is exploring artificial pancreas systems, immunotherapy, and beta cell replacement.
Clinical trials are advancing new treatments for type 1 diabetes. Currently, 100 studies are recruiting a combined 63,273 participants across the United States. Research is being conducted by 70 organizations including Sanford Health, University of Colorado, Denver, University of Florida and 67 others.
2026 Type 1 Diabetes Research Landscape
As of July 2026, the type 1 diabetes clinical trial landscape includes 100 actively recruiting studies across 103 cities in the United States. These studies are collectively seeking 63,273 participants, with an average enrollment target of 633 per study.
The research spans multiple phases of development: 41 studies are in NA, 19 studies are in PHASE2, 8 studies are in PHASE3, 6 studies are in PHASE1, 4 studies are in PHASE4, 4 studies are in EARLY_PHASE1. The presence of Phase 3 trials indicates that some type 1 diabetes treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 70 different organizations, including Sanford Health, University of Colorado, Denver, University of Florida, Insulet Corporation, Beta Bionics, Inc., and 65 others. The large number of sponsors reflects significant research interest and investment in type 1 diabetes treatment advancement.
Geographically, type 1 diabetes trials are most concentrated in Aurora, Colorado (25 trials); Boston, Massachusetts (13 trials); San Francisco, California (12 trials); New Haven, Connecticut (11 trials); Gainesville, Florida (10 trials) and 7 other cities.
Featured Type 1 Diabetes Studies
Highlighted recruiting studies for type 1 diabetes, selected by enrollment size and research scope.
General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery
In partnership with Helmsley Charitable Trust, the Sanford PLEDGE Study is a large-scale, observational, feasibility study of general population screening for T1D and celiac autoantibodies. Screening is incorporated into routine health care visits within an integrated health system.
PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life
This research study is called 'PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life: The PROMISE Study'. The purpose of this study is to find out more about how exposures during pregnancy, such as having an infection, diet and growth may impact later risk of type 1 diabetes (TID) and islet autoimmunity in the child. We are also interested in finding out more about why h...
Immune Function and the Progression to T1D
To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.
Frequently Asked Questions About Type 1 Diabetes Clinical Trials
Are there type 1 diabetes clinical trials near me?
Yes, there are 100 type 1 diabetes clinical trials currently recruiting across 103+ cities in the United States, including Aurora, Colorado; Boston, Massachusetts; San Francisco, California. Browse the studies above to find one at a location convenient for you.
How do I join a type 1 diabetes clinical trial?
To join a type 1 diabetes clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are type 1 diabetes clinical trials free?
Yes, participation in type 1 diabetes clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of type 1 diabetes treatments are being studied?
Current type 1 diabetes clinical trials are testing a range of approaches across NA (41 studies), PHASE2 (19 studies), PHASE3 (8 studies), PHASE1 (6 studies), PHASE4 (4 studies), EARLY_PHASE1 (4 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 70 research organizations.
Is it safe to participate in type 1 diabetes clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 18, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 18, 2026 · Data from ClinicalTrials.gov