Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Osteoporosis Clinical Trials
Osteoporosis clinical trials are recruiting across 28 cities. Here are the cities with the most active studies:
Osteoporosis Trial Phases
16 research organizations are sponsoring osteoporosis trials.
About Osteoporosis
Osteoporosis is a condition that weakens bones, making them fragile and more likely to break. It affects millions of people, particularly postmenopausal women. Treatment includes bisphosphonates, denosumab, calcium/vitamin D supplementation, and anabolic bone agents.
Clinical trials are advancing new treatments for osteoporosis. Currently, 18 studies are recruiting a combined 9,060 participants across the United States. Research is being conducted by 16 organizations including University of Alabama at Birmingham, Johns Hopkins University, Brigham and Women's Hospital and 13 others.
2026 Osteoporosis Research Landscape
As of July 2026, the osteoporosis clinical trial landscape includes 18 actively recruiting studies across 28 cities in the United States. These studies are collectively seeking 9,060 participants, with an average enrollment target of 503 per study.
The research spans multiple phases of development: 9 studies are in NA, 4 studies are in PHASE4, 1 study is in PHASE3, 1 study is in PHASE1, 1 study is in PHASE2. The presence of Phase 3 trials indicates that some osteoporosis treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 16 different organizations, including University of Alabama at Birmingham, Johns Hopkins University, Brigham and Women's Hospital, Wake Forest University Health Sciences, University of Colorado, Denver, and 11 others. The large number of sponsors reflects significant research interest and investment in osteoporosis treatment advancement.
Geographically, osteoporosis trials are most concentrated in Boston, Massachusetts (4 trials); Aurora, Colorado (3 trials); Baltimore, Maryland (2 trials); Winston, Salem-North Carolina (2 trials); Birmingham, Alabama (1 trial) and 7 other cities.
Featured Osteoporosis Studies
Highlighted recruiting studies for osteoporosis, selected by enrollment size and research scope.
RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE
RESTORE tests whether Augmented-FLS, where patients are contacted by a patient navigator (serving as the liaison) and referred to a bone health provider, is better than Enhanced Usual Care, which includes patient and PCP education and activation. We also aim to determine the influence of age, race, ethnicity, sex, poverty level, geographic region, and timing of entry into the trial after a fractur...
Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty
The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is: 1\) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and fragility fractures when compared to standard of care primary care provider referral. Researchers w...
OsteoPorotic fracTure preventION System (OPTIONS) Research Study
Osteoporosis is a disease that weakens bones so the bones may break easily. The risk for osteoporosis increases with age in both women and men. Osteoporosis affects 10 million older adults in the US. Osteoporosis is a common cause of broken bones in the hips and legs. Broken bones can lead to disability, nursing home placement, and death. Because of the dire consequences, a broken hip or leg is on...
Frequently Asked Questions About Osteoporosis Clinical Trials
Are there osteoporosis clinical trials near me?
Yes, there are 18 osteoporosis clinical trials currently recruiting across 28+ cities in the United States, including Boston, Massachusetts; Aurora, Colorado; Baltimore, Maryland. Browse the studies above to find one at a location convenient for you.
How do I join a osteoporosis clinical trial?
To join a osteoporosis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are osteoporosis clinical trials free?
Yes, participation in osteoporosis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of osteoporosis treatments are being studied?
Current osteoporosis clinical trials are testing a range of approaches across NA (9 studies), PHASE4 (4 studies), PHASE3 (1 study), PHASE1 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 16 research organizations.
Is it safe to participate in osteoporosis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov